Results 171 to 180 of about 853,608 (316)

Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells

FEBS Open Bio, EarlyView.
To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai, Yong Xu, Jingjing Ma, Ratchanee Duangrat, Chen Yan, Jingyan Liang, Hua Wei, Bin Jiang, Tao‐Sheng Li   +8 more
wiley   +1 more source

A Survey Study of Patient-Physician Communication and Treatment Decision-Making Preference at Treatment Initiation and After Disease Stabilization in Newly Diagnosed Multiple Myeloma. [PDF]

EJHaem
Hanamoto H, Iino M, Joko K, Kidera K, Yoshida T, Okazuka K, Shibayama H.   +6 more
europepmc   +1 more source

The crystal structure of the Borrelia burgdorferi nicotinamidase BBE22 resolves a long‐standing annotation error

FEBS Open Bio, EarlyView.
The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley   +1 more source

Selective Binding of Hardness Ions by Humic Sorbents for Prevention of Carbonate Scaling in Reverse Osmosis Systems. [PDF]

Molecules
Zhakina AK, Zhakin AM, Vassilets YP, Arnt OV, Muldakhmetov Z.   +4 more
europepmc   +1 more source

Inflation and stabilization in Yugoslavia [PDF]

This paper shows that inflation in Yugoslavia shares common elements with inflation in other highly indebted countries, despite appearances other-wise. These common elements include a large transfer of resources abroad unmatched by an internal adjustment,
Rocha, Roberto de Rezende
core  

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Determinants of hospitalization expenses in primary arthroscopic stabilization for recurrent shoulder anterior instability: A retrospective analysis. [PDF]

Medicine (Baltimore)
Xue J, Wang J, Wu J, Zhao J.
europepmc   +1 more source

Macroeconomic Policies: Stabilization and Transition in Former Czechoslovakia and in the Czech Republic [PDF]

Paper discusses reform process in the Czech Republic (and former Czechoslovakia), which after some preparations in 1990 started in 1991 has been implemented along two major reform lines: - microeconomic restructuring including privatization ...
Miroslav Hrncir, Jan Klacek
core  

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

FEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay, Junjie Xu, Josep Rizo   +2 more
wiley   +1 more source

Enhancing graft stability in coronally advanced tunnel with connective tissue graft for Cairo RT1 and RT2 gingival recession: a case series. [PDF]

J Surg Case Rep
Khursheed DA.
europepmc   +1 more source