Results 61 to 70 of about 62,313 (219)

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

MAGNETIC INVERSION TO RECOVER COMPACT STRUCTURES BY AN ARCTANGENT STABILIZER

open access: yesRudarsko-geološko-naftni Zbornik
This study introduces a novel method for the inversion of magnetic data using a focusing inversion technique. The method utilizes an arctangent stabilizing functional, which is reformulated into a pseudo-quadratic form by a weighting matrix.
Sahar Moazam, Mohammad Rezaie
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

APLIKASI NATRIUM CARBOXYMETHYL CELLULOSE (NA-CMC) DARI KULIT KACANG KEDELAI SEBAGAI PENSTABIL YOGHURT SUSU SAPI

open access: yesJurnal Pangan dan Agroindustri
ABSTRAK Keberadaan selulosa dalam kulit kacang kedelai memiliki potensi dalam pembuatan Na-CMC. Penambahan Na-CMC kulit kacang kedelai pada yoghurt susu sapi dapat mencegah terjadinya sineresis. Penelitian ini bertujuan untuk memanfaatkan limbah
Chapib Jamaludin   +3 more
doaj   +1 more source

Pengaruh Konsentrasi kappa Karaginan Pada Es Krim Terhadap tingkat Kesukaan Panelis

open access: yesJurnal Pascapanen dan Bioteknologi Kelautan dan Perikanan, 2007
Penelitian ini bertujuan untuk mengetahui tingkat kesukaan panelis terhadap es krim yang dibuat dari : gula 20%, susu kental manis 13%, santan kelapa 13%, tepung maizena 2,5%, tepung tapioka 1%, air 50%, flavor, essence dan garam secukupnya serta ...
Ellya Sinurat   +2 more
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Simultaneous Determination of Two Stabilizers Content in Lutetium[177Lu] Oxodotreotide Injection by High-Performance Liquid Chromatography

open access: yesHe huaxue yu fangshe huaxue
A high-performance liquid chromatography(HPLC) was established for the determination of stabilizer(gentisic acid, vitamin C) content in lutetium[177Lu] oxodotreotide injection.
Yong WANG   +10 more
doaj   +1 more source

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