Results 61 to 70 of about 20,866 (243)

Universal fault-tolerant quantum computing with stabilizer codes

Physical Review Research, 2022
The quantum logic gates used in the design of a quantum computer should be both universal, meaning arbitrary quantum computations can be performed, and fault-tolerant, meaning the gates keep errors from cascading out of control.
Paul Webster, Michael Vasmer, Thomas R. Scruby, Stephen D. Bartlett   +3 more
doaj   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Hybrid Oscillator-Qudit Quantum Processors: Stabilizer States, Stabilizer Codes, Symplectic Operations, and Noncommutative Geometry

PRX Quantum
We construct stabilizer states and error-correcting codes on hybrid discrete- and continuous-variable systems, generalizing the Gottesman-Kitaev-Preskill (GKP) lattice formalism.
Sayan Chakraborty, Victor V. Albert
doaj   +1 more source

Subsystem CSS codes, a tighter stabilizer-to-CSS mapping, and Goursat's Lemma [PDF]

Quantum
The CSS code construction is a powerful framework used to express features of a quantum code in terms of a pair of underlying classical codes. Its subsystem extension allows for similar expressions, but the general case has not been fully explored ...
Michael Liaofan Liu, Nathanan Tantivasadakarn, Victor V. Albert   +2 more
doaj   +1 more source

Stabilizer codes from modified symplectic form

, 2018
Stabilizer codes form an important class of quantum error correcting codes which have an elegant theory, efficient error detection, and many known examples. Constructing stabilizer codes of length $n$ is equivalent to constructing subspaces of $\mathbb{F}
Gandhi, Tejas, Kurur, Piyush, Mittal, Rajat   +2 more
core   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Fault-Tolerant Logical Clifford Gates from Code Automorphisms

PRX Quantum
We study the implementation of fault-tolerant logical Clifford gates on stabilizer quantum error-correcting codes based on their symmetries. Our approach is to map the stabilizer code to a binary linear code, compute its automorphism group, and impose ...
Hasan Sayginel, Stergios Koutsioumpas, Mark Webster, Abhishek Rajput, Dan E. Browne   +4 more
doaj   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source