Results 171 to 180 of about 55,201 (251)

Real‐world persistence and dose titration of GLP‐1 receptor agonists in type 2 diabetes: A UK population‐based cohort study by obesity and cardiovascular disease status

open access: yesDiabetes, Obesity and Metabolism, Volume 28, Issue 4, Page 3386-3395, April 2026.
Abstract Aims Real‐world medication use varies across clinical trial and healthcare settings; therefore, we evaluated GLP‐1 receptor agonist (GLP‐1RA) persistence and dose titration among adults with type 2 diabetes in UK primary care, stratified by agent, obesity status, cardiovascular disease (CVD) history, and sex assigned at birth.
Franziska S. Ulrich   +3 more
wiley   +1 more source

Integrating gepants into clinical practice for the acute treatment of migraine

open access: yesHeadache: The Journal of Head and Face Pain, Volume 66, Issue 4, Page 976-989, April 2026.
Abstract Objective To assess the role of small‐molecule calcitonin gene–related peptide receptor antagonists (gepants) in the acute treatment of migraine, particularly in relation to triptan treatments. Background Triptans have established efficacy and are widely prescribed for the acute treatment of migraine.
Richard B. Lipton   +4 more
wiley   +1 more source

Association Between Obesity Status and Hypertension Phenotypes: Are Inflammatory Indicators the Missing Link? Evidence From a Large Population Study

open access: yesThe Journal of Clinical Hypertension, Volume 28, Issue 4, April 2026.
ABSTRACT Hypertension exhibits variability in diagnosis and treatment across phenotypes. Obesity and metabolic disorders are key risk factors, interacting with inflammatory states. This study explores their associations with hypertension phenotypes and the mediating role of inflammation.
Xue Li   +4 more
wiley   +1 more source

Bedroom Air Filtration and Home Blood Pressures of Older Adults Living in a Residential Facility

open access: yesThe Journal of Clinical Hypertension, Volume 28, Issue 4, April 2026.
ABSTRACT Portable air cleaners (PACs) can reduce blood pressure (BP) by decreasing fine particulate matter (PM2.5) air pollution exposure. However, the effectiveness of a single PAC in a bedroom and the impact on self‐measured home BPs over 4 weeks have not been evaluated.
Robert D. Brook   +9 more
wiley   +1 more source

Sex differences in cerebrovascular function across an aerobic exercise intervention in older adults using MRI: Results from the Brain in Motion study

open access: yesPhysiological Reports, Volume 14, Issue 8, April 2026.
Females and males differ in their cerebral blood flow changes across an aerobic exercise intervention in the regions of the hippocampi, insula, and left pars triangulars. Abstract Sex differences in cerebral blood flow (CBF) and cerebrovascular reactivity (CVR) with aging, and across an aerobic exercise training intervention are poorly understood.
Alison M. H. Donald   +6 more
wiley   +1 more source

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