ABSTRACT Mass cytometry is optimal for acute leukemia immune checkpoint profiling. However, current commercial metal‐chelating polymer (MCP) metal tags limit its sensitivity due to low metal loading capacity. We report a novel synthetic strategy employing antibody‐conjugated gold or platinum nanoparticles (AuNP/PtNP) for high‐dimensional single‐cell ...
Zhizhou Liu +8 more
wiley +1 more source
Effects of Seasonings on the Stable Isotope Analysis of Protein Fractions in Cooked Beef: A Preliminary Study for Geographical Origin Purposes. [PDF]
Suzuki Y +4 more
europepmc +1 more source
This work provides an effective strategy for selectively extracting 212Pb and 212Bi from the decay chain of 232Th as well as its mechanism illustration. Using the novel strategy, 2.07 MBq of 212Pb is successfully separated from 232Th and its daughters, which enables the supply of 212Pb/212Bi directly from the abundant natural thorium resource to be ...
Lifeng Chen +11 more
wiley +1 more source
Investigating human paleodiet at Mesolithic Yuzhniy Oleniy Ostrov, Karelia using a multi-proxy stable isotope approach. [PDF]
Eckelmann RII +9 more
europepmc +1 more source
Nanoscale secondary ion mass spectrometry (Nano SIMS) is established as a powerful analytical tool to visualize and quantify the membrane fouling layers. ABSTRACT Membrane technology has garnered considerable attention for applications in wastewater treatment and resource recovery. Nevertheless, membrane fouling remains a major barrier, yet the lack of
Mengfei Wu +4 more
wiley +1 more source
Protocol for identifying the BZR1 interactome under starvation in Arabidopsis by metabolic stable isotope labeling quantitative IP-MS. [PDF]
Zhang Z, Wang ZY.
europepmc +1 more source
Post‐Translational Regulation of CD8+ T Cell Fate and Dysfunction in Tumor Immunity
This review delineates how post‐translational modifications (PTMs) function as a central regulatory interface governing CD8+ T cell activation, differentiation, persistence, and exhaustion in antitumor immunity. By integrating antigenic, metabolic, and microenvironmental cues, diverse PTM programs coordinate transcriptional and chromatin states that ...
Zihao Zhou +8 more
wiley +1 more source
Stable isotope and multi-elemental analysis combined with statistical modeling for saffron origin authentication. [PDF]
Terro C +10 more
europepmc +1 more source
OsGSK2‐OsTCP19 module regulating nitrate response and lateral root (LR) development. Low‐nitrate condition results in reduced BR response, accumulation of OsGSK2 and phosphorylated OsTCP19, which suppresses the expression of nitrate‐responsive genes and LR‐development genes and impairs rice growth.
Yongqiang Liu +11 more
wiley +1 more source
Discovery of Suomilide and Cyanopeptolin Analogues by <sup>15</sup>N Stable Isotope Labeling and Genome Mining of Cyanobacteria. [PDF]
Chauvin IM +3 more
europepmc +1 more source

