Results 41 to 50 of about 1,883,366 (248)
Smaller is better: nanobodies meet NMR
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Content, composition, and transfer of polyunsaturated fatty acids in an Arctic lake food web
Freshwater fish production depends on the production and use of polyunsaturated fatty acids (n‐3 and n‐6 PUFA) from lower trophic levels. Here, we aimed to identify the main trophic pathways that support PUFA content in different fish species (mean 39.7 ...
Guillaume Grosbois +4 more
doaj +1 more source
Stable isotopic labeling in proteomics [PDF]
AbstractLabeling of proteins and peptides with stable heavy isotopes (deuterium, carbon‐13, nitrogen‐15, and oxygen‐18) is widely used in quantitative proteomics. These are either incorporated metabolically in cells and small organisms, or postmetabolically in proteins and peptides by chemical or enzymatic reactions.
Gevaert, Kris +5 more
openaire +3 more sources
Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana +5 more
wiley +1 more source
The separation of stable isotope carbon-13(13C) is very difficult because the separation coefficient is only 1.007. So it is necessary that nearly three thousand theoretical stages should be required to obtain a high abundance product of 99 atom% 13C. In
TIAN Yesheng;LI Hulin
doaj +1 more source
A 15N stable isotope semen label to detect mating in the malaria mosquito
In previous studies it was determined that the stable isotope 13-carbon can be used as a semen label to detect mating events in the malaria mosquito Anopheles arabiensis. In this paper we describe the use of an additional stable isotope, 15-nitrogen (15N)
Hood Rebecca C +9 more
core +1 more source
Solvate ionic liquids lubrication reduced the coefficient of friction by ∼60% compared to dry sliding, reaching steady‐state values as low as 0.04–0.05. Corrosion weight‐loss measurements in 1 M HCl further demonstrated significant inhibition behavior, with only 100 ppm of [Li(G3)][TFSI] (∼68.5 μL/L) reducing corrosion‐product weight loss by 63 ...
Sameh Dabees +6 more
wiley +1 more source
Testing a dual isotope model to track carbon and water gas exchanges in a Mediterranean forest
Due to climate change, drier summers have been observed over the last ten years in Mediterranean areas. Increasing drought levels may have a different weight in influencing the stomatal versus photosynthetic activity of forests, altering the water-use ...
Ripullone F +6 more
doaj +1 more source
Near‐surface deuterium enrichment profiles for different microstructural types of TiAl after exposure at 700 °C in a heavy water‐containing environment. The deuterium levels are significantly higher than expected from natural occurrence, indicating that the heavy water dissociated during the exposure treatment and entered the specimens.
Jonathan D. H. Paul +5 more
wiley +1 more source

