Results 41 to 50 of about 100,245 (263)
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Testing a dual isotope model to track carbon and water gas exchanges in a Mediterranean forest
iForest - Biogeosciences and Forestry, 2009 Due to climate change, drier summers have been observed over the last ten years in Mediterranean areas. Increasing drought levels may have a different weight in influencing the stomatal versus photosynthetic activity of forests, altering the water-use ...
Ripullone F +6 more
doaj +1 more source
Syntheses of Stable Isotope ［13C］/D Labelled p-Methoxybenzoic Acid
Journal of Isotopes, 2020 Stable isotope labelled p-methoxybenzoic acid is an important intermediate in the synthesis of stable isotope labelled preservative, anti-microbial, anti-fungal, spices, and other internal standard reagentsspices, drugs and other compounds.
WANG Wei;DU Xiaoning;XU Jianfei;LEI Wen
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
CSF Monoamine Metabolites and Cognitive Trajectory in Early Parkinson's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Imaging and postmortem studies indicate that abnormalities in monoaminergic neurotransmission contribute to cognitive impairment in Parkinson's disease (PD). However, it remains uncertain if cerebrospinal fluid (CSF) monoamine metabolites can serve as biomarkers of cognitive decline in early PD.
Jing‐Yu Shao +7 more
wiley +1 more source
Advanced Engineering Materials, EarlyView.This review highlights advances in lightweight, lead‐free polymer nanocomposites for diagnostic X‐ray shielding. By linking filler chemistry, dispersion, architecture, and photon interaction mechanisms, it establishes structure–performance relationships guiding material design.
Aklilu G. Messele +2 more
wiley +1 more source
Labrador Sea freshening at 8.5 ka BP caused by Hudson Bay Ice Saddle collapse
Nature Communications, 2019 The exact freshwater scenario that caused the 8.2 ka cold event is still debated. This study presents new evidence for a severe Labrador shelfwater freshening 8500 years ago that was caused by the Hudson Bay Ice Saddle collapse following a warming in ...
Annalena Antonia Lochte +6 more
doaj +1 more source
Synthesis of Stable Isotope Deuterium Labeled Levofloxacin-D3
Journal of Isotopes, 2023 In order to improve the stable isotope utilization rate, a simple and inexpensive synthesis method was developed. The synthesis of levofloxacin is based on piperazine as the starting material, and the reaction with carbobenzoxy chloride (CBZ-Cl) to get ...
XU Zhong jie;ZHANG Li;SUN Wen;ZHANG Pengshuai;LEI Wen
doaj +1 more source
Advanced Functional Materials, EarlyView.Controlling the exposed crystal facet of shape‐controlled Au‐Pd core‐shell catalysts though colloidal synthesis enhances their catalytic performance in the industrially relevant selective hydrogenation of butadiene. ABSTRACT Selective hydrogenation of butadiene is a critical step in purification of alkene feedstocks for polymer production and is ...
Marta Perxés Perich +3 more
wiley +1 more source
Life, 2020 Energy derived from water-rock interactions such as serpentinization and radiolysis, among others, can sustain microbial ecosystems deep within the continental crust, expanding the habitable biosphere kilometers below the earth’s surface.
Regina L. Wilpiszeski +3 more
doaj +1 more source