Results 51 to 60 of about 268,489 (347)

Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky, Cara Joyce, H. Jeremy Bockholt, Paul A. Rudnick, William H. Adams, Fiona McAllister, Justin W. Smock, Michael A. Newton, Jane S. Paulsen   +8 more
wiley   +1 more source

CSF Monoamine Metabolites and Cognitive Trajectory in Early Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Imaging and postmortem studies indicate that abnormalities in monoaminergic neurotransmission contribute to cognitive impairment in Parkinson's disease (PD). However, it remains uncertain if cerebrospinal fluid (CSF) monoamine metabolites can serve as biomarkers of cognitive decline in early PD.
Jing‐Yu Shao, Rong Li, Yu‐Xiang Jiao, Kai Ma, Hong‐Qi Yang, Zheng‐Yu Sun, Jie‐Wen Zhang, Shuai Chen   +7 more
wiley   +1 more source

Mercury Isotopes in Shale Gas From Wufeng-Longmaxi Shale Formation of Sichuan Basin, Southern China: A Preliminary Investigation

Frontiers in Earth Science, 2022
A series of investigations have been conducted concerning the study of traditional stable isotopes and rare gas stable isotopes in natural gas. However, little is known regarding non-traditional stable isotopes of mercury in natural gas, especially in ...
Shunlin Tang, Yuxiang Ding, Guangyou Zhu, Xinbin Feng, Huaishun Zhang, Penggao Li   +5 more
doaj   +1 more source

Selective and Precise Editing of Digital Polymers Through Parallel or Series Toehold‐Mediated Strand Displacement

Advanced Functional Materials, EarlyView.
A sequence‐encoded supramolecular construct containing two accessible toeholds is developed herein for enabling multiple editing operations. By introducing specific input strands, it is possible to selectively erase or rewrite digital content through parallel or series toehold‐mediated strand displacement (PTMSD or STMSD).
Jakub Ossowski, Cyril Antheaume, Jean‐François Lutz, Maria Nerantzaki   +3 more
wiley   +1 more source

The vertical distribution of iron stable isotopes in the North Atlantic near Bermuda [PDF]

, 2012
Seawater dissolved iron isotope ratios (δ^(56)Fe) have been measured in the North Atlantic near Bermuda. In a full-depth profile, seawater dissolved δ^(56)Fe is isotopically heavy compared to crustal values throughout the water column (δ^(56)Fe_(IRMM-014)
Adkins, Jess, John, Seth G.
core   +1 more source

Electroactive Metal–Organic Frameworks for Electrocatalysis

Advanced Functional Materials, EarlyView.
Electrocatalysis is crucial in sustainable energy conversion as it enables efficient chemical transformations. The review discusses how metal–organic frameworks can revolutionize this field by offering tailorable structures and active site tunability, enabling efficient and selective electrocatalytic processes.
Irena Senkovska, Yutong Luo, Ruyan Zhao, Jianjun Zhang, Mingchao Wang, Xinliang Feng, Eike Brunner, Stefan Kaskel   +7 more
wiley   +1 more source

Tracing sheep binary C3–C4 diet using stable isotope ratio (δ13C)

Italian Journal of Animal Science, 2021
Stable isotopes are an important tool to assess livestock diet in binary mixtures of C3-C4 forages. However, the use of stable isotopes to trace livestock diet using tropical arboreal legumes has been limited.
Kariny Cavalcante de Lira, José Carlos Batista Dubeux, Mário de Andrade Lira, Francisco Fernando Ramos Carvalho, Mércia Virgínia Ferreira Santos, Márcio Vieira Cunha, Alexandre Carneiro Leão Mello, David M. Jaramillo, José Diogenes Pereira Neto   +8 more
doaj   +1 more source

An integrated mineralogical, petrographic, light stable isotope and noble gas investigation of Sahara 99201 ureilite [PDF]

, 2001
New ureilite Sahara 99201 has been investigated to determine mineralogy, petrography, light stable isotopes and noble gases. The sample is a typical olivine pigeonite ureilite (Fo 78, Wo 10, En 72).
Franchi, Ian, Grady, Monica, Pillinger, Colin, Smith, C. L., Verchovsky, Sasha, Wright, Ian   +5 more
core  

SI‐bioATRP in Mesoporous Silica for Size‐Exclusion Driven Local Polymer Placement

Advanced Functional Materials, EarlyView.
An enzyme‐catalyzed surface‐initiated atom transfer radical polymerization (SI‐bioATRP) of an anionic monomer within mesoporous silica particles, using hemoglobin as a catalyst, allows for controlling the location of the formed polymer via size‐exclusion effects between the nanopores and the biomacromolecules, thereby opening routes to functional ...
Oleksandr Wondra, Eleonora Ornati, Robert Lehn, Joanna J. Mikolei, Hergen Breitzke, Raheleh Pardehkhorram, Gerd Buntkowsky, Nico Bruns, Annette Andrieu‐Brunsen   +8 more
wiley   +1 more source

Komposisi Isotop Stabil dan Trofik Level Kerang Kipas (Pectenidae: Chlamydinae sp.) dan Produsen Primer di Pulau Pari, Kepulauan Seribu, DKI Jakarta

Al-Kauniyah Jurnal Biologi, 2013
Scallop (Pectenidae: Chlamydinae sp.) is fauna habitat in seashore ecosystem and had commercial value commudity. The aims this study were to identify the main composition of stable isotopes, food sources, and trophic level from scallop and potential food
Mardiansyah Mardiansyah, Yusli Wardiatno, Tri Prartono   +2 more
doaj   +1 more source