Results 131 to 140 of about 1,239,268 (312)

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Integrability of Stable Processes [PDF]

open access: yes, 1990
Abstract : Let nu be a alpha-finite Borel measure on a separable metric space T, and let (X(t) t epsilon T) be a measurable alpha-stable process ...
openaire   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Spatial modeling of extreme temperature in the Canadian Prairies using max-stable processes

open access: yesResults in Engineering
The Prairie region of Canada is an agriculture-intensive area and is strategic to Canada's food security. Moisture deficit due to extreme temperatures leading to high evapotranspiration can have significant impacts on water availability, resulting in ...
Alaba Boluwade   +2 more
doaj   +1 more source

On the Lamperti stable processes

open access: yes, 2008
6 ...
Caballero, M. E.   +2 more
openaire   +2 more sources

Stable isotopes and biosphere-atmosphere interactions : processes and biological controls /

open access: yes, 2005
The emerging multidisciplinary field of earth system science sets out to improve our understanding functioning ecosystems, at a global level across the entire planet.
Ehleringer, J. R.   +2 more
core  

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Approximation of stochastic differential equations driven by alpha-stable Levy motion [PDF]

open access: yes
In this paper we present a result on convergence of approximate solutions of stochastic differential equations involving integrals with respect to alpha-stable Levy motion.
Aleksander Janicki   +2 more
core  

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Mixing of water in a carbonate aquifer, southern Italy, analysed through stable isotope investigations

open access: yesInternational Journal of Speleology, 2013
Mixing of water was analysed in a carbonate aquifer, southern Italy, through stable isotope investigations (18O,δ2H). The input signal (rainwater) was compared with the isotopic content of a 35-meter groundwater vertical prof ile, over a 1-year period ...
Petrella Emma, Celico Fulvio
doaj  

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