Results 91 to 100 of about 12,979,380 (326)

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

An investigation on artificial reproduction of Mugil cephalus

open access: yes‬‭Majallah-i ̒Ilmī-i Shīlāt-i Īrān, 2005
Cultured nine years old breeder M. cephalus specimens were subjected to eight artificial breeding treatments from December till February 2003. In treatments 1-5, breeders received two injections of CPH and LIIRFI—A2 coupled with Domperidone or a mixture ...
A. Mirhashemi rostami; K. Amini; M. Jorjani; H. Gholi ghezel; A. Shafeei
doaj  

Stages of formation the russian system of antimoney laundering

open access: yesПутеводитель предпринимателя, 2020
The paper studies the main stages of formation of the Russian system of struggle against money-laundering since 1989and on the present moment. Considers practical aspects of struggle against money-laundering, structures, developed on the development ...

doaj  

Morphological and histological studies on the reproductive system of Puntius sarana sarana (Hamilton, 1822) (Cyprinidae)

open access: yesEnvironment Conservation Journal, 2018
The objective of the present study was to describe the phases of gonadal of P.sarana sarana under captive conditions. The different stages of oogenesis and spermatogenetic development were examined microscopically.
Mansoor Ahmad Rather   +2 more
doaj   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

New Characterization of Lipedema Stages: Focus on Pain, Water, Fat and Skeletal Muscle

open access: yesLife
Lipedema is a chronic, progressive adipose connective tissue disorder characterized by symmetrical, disproportionate fat accumulation, typically affecting the lower extremities and arms, accompanied by pain, swelling, and a sensation of heaviness.
Sara Al-Ghadban   +3 more
doaj   +1 more source

Technological bases of projecting distance learning courses

open access: yesCTE Workshop Proceedings, 2017
The purpose of the research: determining the technological basis for projecting distance learning courses. Objectives of the research: structuring technology projecting distance learning courses in stages; determination of the nature and characteristics
A. O. Kucheriavyi
doaj   +1 more source

Early Stages of Fatigue Damage of Steels for Fusion Energetics [PDF]

open access: yes, 2012
Hlavním cílem této práce bylo vysvětlit únavové chování ocelí ODS Eurofer, 14Cr ODS feritické oceli vyráběné v CEA (Commissariat a l’énergie atomique, Saclay, France) a 14Cr ODS feritické oceli vyráběné v EPFL (École Polytechnique Fédérale de Laussane ...
Kuběna, Ivo
core  

Strategic delegation in a sequential model with multiple stages

open access: yes, 2012
We analyze strategic delegation in a Stackelberg model with an arbitrary number, n, of firms. We show that the n-1 last movers delegate their production decisions to managers whereas the first mover does not. Equilibrium incentive rates are increasing in
Fershtman C.   +3 more
core   +1 more source

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