Results 201 to 210 of about 2,539,095 (269)

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Mutation of STAY-GREEN 1 in tomato increases volatile organic compounds during fruit ripening. [PDF]

Plant Cell Physiol
Chun JI, Han GH, Kim SY, Kim SM, Kim GJ, Kim B, Kim JK, Cho JY, Kim HY, Kang JH.   +9 more
europepmc   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Tracking U.S. Liquefied Natural Gas Supply Chain Greenhouse Gas Emission Intensity through Direct Measurements. [PDF]

Environ Sci Technol
Zhu Y, Ross GB, Brown J, Khaliukova O, Daniels W, Wang J, Roman-White S, George FC, Zimmerle D, Hammerling D, Ravikumar AP.   +10 more
europepmc   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Mass spectrometry-based proteomics to study gastric carcinogenesis: pathophysiological molecular characterization. [PDF]

Sci Rep
Felípez N, Montori S, Valero A, Santamaría E, Ausin K, Peral E, Llach J, Delgado P, Florez-Diez P, Barreiro E, Arruebo E, Vicente R, Soria M, Huerta A, Ortega SP, Núñez H, Díez P, Herreros A, Hontoria G, Saiz RM, Hernández L, Mangas-Sanjuan C, Patrón O, Hijos-Mallada G, Domper-Arnal MJ, Zarraquiños S, Díez-Martín AI, Gonçalves P, de Frutos D, Santiago J, García A, Martín-Lagos A, Estremera-Arévalo F, Gómez-Alonso M, Cuestas A, Balaguer F, Castellví-Bel S, Fernandez-Esparrach G, Cuatrecasas M, Moreira L, Fernández-Irigoyen J, Albéniz E, EpiGASTRIC EDGAR Consortium.   +42 more
europepmc   +1 more source

Mediating effect of insulin resistance in the relationship between dietary inflammatory index and cardiovascular-kidney-metabolic syndrome stage in US adults, 2007-2018. [PDF]

Food Nutr Res
Xiao Y, You H, Wang T, Zeng Y, Zhu Y, Zhang R, Liu D, Zhao Y, Liu Y, You S, Qiao B, Yuan J, Yang W.   +12 more
europepmc   +1 more source

Impact of the COVID-19 pandemic on hepatitis C care across the cascade of care: a scoping review. [PDF]

BMC Infect Dis
Lamadrid A, Leiva-Escobar I, Soza A, Quentin W.   +3 more
europepmc   +1 more source

Developmental Stage-Dependent Stoichiometric Characteristics of Fine Roots and Their Relationship with Soil Nutrients in <i>Caragana tibetica</i> Shrubs in a Desert Steppe Ecosystem. [PDF]

Plants (Basel)
Liang Y, Liu L, Han M, Tian Q, Yuan L, Gao Y.   +5 more
europepmc   +1 more source

Pulmonary lesions reshape swine respiratory microbiota: evidence of bacterial dysbiosis and reduced diversity. [PDF]

Braz J Microbiol
Rodeghiero K, Breyer GM, Takeuti KL, Siqueira FM.   +3 more
europepmc   +1 more source