Results 201 to 210 of about 376,984 (269)

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Augmenting Large Language Model With Prompt Engineering and Supervised Fine-Tuning in Non-Small Cell Lung Cancer Tumor-Node-Metastasis Staging: Framework Development and Validation. [PDF]

JMIR AI
Jin R, Ling C, Hou Y, Sun Y, Li N, Han J, Sheng J, Wang Q, Liu Y, Zheng S, Ren X, Chen C, Wang J, Li C.   +13 more
europepmc   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Correction to: Optimizing patient triage on the waiting list for transcatheter aortic valve replacement: the clinical utility of the cardiac damage staging system. [PDF]

Eur Heart J Qual Care Clin Outcomes
europepmc   +1 more source

Optimizing gastric cancer treatment: the role of LODDs in lymph node staging. [PDF]

Front Oncol
Hao Z, Niu H, Bi Y, Sun Q, Yang W.
europepmc   +1 more source

Educational Case: Hidradenitis suppurativa. [PDF]

Acad Pathol
Saal RC, Westerkam LL, Carrasco Mendoza CA, Googe PB, Sayed CJ.   +4 more
europepmc   +1 more source

Computed tomography staging of colon cancer: improved patient selection for neoadjuvant therapy with combined radiologic tumor and nodal staging. [PDF]

BMC Cancer
Lee S, Yu J, Kampalath R, Castillo O, Sandhu J, Tajik F, Ostowari A, Kirby KA, Dehkordi-Vakil FH, Chantaduly C, Chang PD, Vilchez V, Straker RJ, Whealon MD, Krishnamurthi SS, Maithel SK, Stamos MJ, Senthil M.   +17 more
europepmc   +1 more source

Decoding the 2023 FIGO Staging System in Endometrial Cancer: A Practical, Visually Guided Framework for Molecular Risk-Adapted Care Incorporating the 2025 Risk Group Update. [PDF]

Curr Oncol Rep
Abacjew-Chmylko A, Razghоnоva Y, Milosz P, Ciarka A, Peksa R, Klasa-Mazurkiewicz D, Wydra DG, Mіka A.   +7 more
europepmc   +1 more source

Performance of GPT-based large language models in hepatocellular carcinoma stratification: liver function assessment, BCLC staging, and treatment recommendations. [PDF]

Sci Rep
Masthoff M, Zipser A, Praktiknjo M, Trebicka J, Morgül H, Pascher A, Pöhler G, Köhler M, Schindler P.   +8 more
europepmc   +1 more source