Results 111 to 120 of about 5,337,721 (395)
Recent Advancements in Lung Cancer Metastasis Prevention Based on Nanostrategies
Advanced Science, EarlyView.Metastasis is the leading cause of death in patients with lung cancer. Nanomedicine can be used to prepare efficient drug delivery systems owing to their advantages and plays an important role in the synergistic antimetastasis of lung cancer. This comprehensive review summarizes the emerging nanostrategies against lung cancer metastasis based on the ...
Fan Xu +7 more
wiley +1 more source
Influence of High Pressure Drop Rates on Fatigue Crack Growth
Chemical Engineering &Technology, Volume 46, Issue 1, Page 45-52, January 2023., 2023 Hydraulic components are subjected to varying loads, limiting their lifetime. Accelerating fatigue studies through high‐frequency pulsation would decrease costs and time to market. However, the fluid‐structure interaction causes a time‐dependent fatigue load.
Lukas Michiels, Marcus Geimer
wiley +1 more source
Advancing Allogeneic NK Cell Immunotherapy through Microfluidic Gene Delivery
Advanced Science, EarlyView.The Y‐Hydroporator is a microfluidic gene delivery platform designed for allogeneic NK cell‐based immunotherapies. It achieves highly efficient gene delivery while preserving high cell viability and functionality. By producing engineered NK cells with enhanced cytotoxicity, the platform addresses critical limitations of autologous cell therapy ...
Hyelee Kim +6 more
wiley +1 more source
CPL‐Diff: A Diffusion Model for De Novo Design of Functional Peptide Sequences with Fixed Length
Advanced Science, EarlyView.This study presents a diffusion model for generating functional peptide sequence lengths using mask control. The model can generate antimicrobial, antifungal, and antiviral peptides with specific lengths on demand. The model learns the structure of peptides better and generates peptides with better physicochemical properties, and the model has good ...
Zhenjie Luo +5 more
wiley +1 more source
Advanced Science, EarlyView.Diallyl trisulfides (DATs) selectively induce cuproptosis in hepatic stellate cells (HSCs) by targeting Ras‐related protein Rab‐18 (RAB18) and regulating lipophagy. DATs promote RAB18 phase separation, enhance mitochondrial‐associated membrane structures (MAMs) formation, and increase succinylation of dihydrolipoamide dehydrogenase (DLD) at K320.
Haoyuan Tian +16 more
wiley +1 more source
A remote hypertension management program clinical algorithm
Clinical Cardiology, Volume 45, Issue 12, Page 1147-1162, December 2022., 2022 Abstract Introduction Hypertension is the leading risk factor for death, affecting over one billion people worldwide, yet control rates are poor and stagnant. We developed a remote hypertension management program that leverages digitally transmitted home blood pressure (BP) measurements, algorithmic care pathways, and patient–navigator communications ...
Hunter Nichols +3 more
wiley +1 more source
Tailored 3D Lattice Microstructures for Enhanced Functionality in Blood‐Gas Exchange
Advanced Science, EarlyView.Common hollow fiber structures are associated with inhomogeneous flow, leading to many complications in the medical application of extracorporeal membrane oxygenation. Using locally adapted lattice structures, the overall flow distribution can be manipulated.
Kai P. Barbian +10 more
wiley +1 more source
Stagnation–saddle points and flow patterns in Stokes flow between contra-rotating cylinders [PDF]
, 1998 The steady flow is considered of a Newtonian fluid, of viscosity mu, between contra-rotating cylinders with peripheral speeds U-1 and U-2 The two-dimensional velocity field is determined correct to O(H-0/2R)(1/2), where 2H(0) is the minimum separation of
Gaskell, P.H. +2 more
core +1 more source
Stagnation point flow with radiation [PDF]
Coupling between inviscid and viscid flows in hypersonic stagnation region investigated at high flight velocities with significant radiative heat ...
Chisnell, R. F. +2 more
core +1 more source