Results 121 to 130 of about 2,042,513 (399)

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

IMPLEMENTASI PENDEKATAN SCIENTIFIC DALAM PENGAJARAN BAHASA INGGRIS KURIKULUM 2013 DI SMPN 1 PAMEKASAN

Okara: Jurnal Bahasa dan Sastra, 2015
This article is a summary of a group research describing the implementation of scientific approach in teaching English of Curriculum 2013 at SMPN 1 Pamekasan.
Siti Azizah, Eko Ariwidodo, Iswah Adriana   +2 more
doaj   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

Pengembangan dan Pembangunan Destinasi Halal Pantai Rupat dalam Peningkatan Pendapatan Masyarakat Rupat

Krigan
Secara umum, sektor pariwisata dikembangkan oleh pemerintah konvensional, sementara itu yang Syariah tidak banyak berkembang. Wisata halal Islami sangat mendukung nilai-nilai keislaman yang berlandaskan Al Quran dan bersifat Sunnah.
Joni Hendra Joni, Faridatul Munawarah, Silfi Amelia Riski, Endang Suwariya   +3 more
doaj   +1 more source

PENINGKATAN KETERAMPILAN BERBICARA BAHASA INGGRIS DENGAN METODE SUGGESTOPEDIA PADA MAHASISWA SEMESTER II-E TBI STAIN PAMEKASAN

Okara: Jurnal Bahasa dan Sastra, 2015
There are two problems in the result of research that will be discussed in this article. They are (1) how are the steps of the implementation of suggestopedia method in learning speaking English at the second semester students of E class TBI STAIN ...
Sumihatul Ummah, Eko Ariwidodo, Afifah Raihany   +2 more
doaj   +1 more source

Organic contamination of LDEF [PDF]

A brown stain of varying thickness was present on most of the exterior surface of the retrieved Long Duration Exposure Facility (LDEF). Tape lifts of Earth-end LDEF surfaces taken in Feb.
Harvey, Gale A.
core   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

Kajian Islam Nusantara Bugis di Perguruan Tinggi Islam Negeri: studi pada UIN Alaudin Makasar, STAIN Watampone dan STAIN Palopo [PDF]

, 2013
Kajian Islam Bugis di UIN Makasar, STAIN Watampone dan STAIN Palopo memiliki dinamika dan berbagai varian kajian. Varian pertama adalah kajian sejarah dan perkembangan Islam serta proses Islamisasi di Sulawesi Selatan di mana masyarakat Bugis menjadi ...
Bahar, M. Syaeful, Chalik, Abdul
core  

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Identifying Key Predictors of Academic Engagement in Low-Performing Schools: The Interplay Between Social Context and Psychological Factors

Edukasia
Research shows that students’ academic engagement is influenced by both social and psychological factors. This study aims to explore which aspects of social context (family, school, and community), and psychological traits (self-efficacy, perseverance ...
Bulqia Mas'ud, Zulfianah Sunusi, Zuhdiah Zuhdiah, Okky Naomi Sahupala   +3 more
doaj   +1 more source