Results 151 to 160 of about 1,168,682 (357)

RKIP overexpression reduces lung adenocarcinoma aggressiveness and sensitizes cells to EGFR‐targeted therapies

Molecular Oncology, EarlyView.
RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha, Joana Pinheiro, Rui F. Marques, Patrícia Fontão, Diana Cardoso‐Carneiro, Adriana Mendes, Izabela N. F. Gomes, Ana Carolina Laus, Renato J. da Silva‐Oliveira, Rui Manuel Reis, Olga Martinho   +10 more
wiley   +1 more source

Socio-Intellectual Construction of Mandailing Clerics in the 20th Century and Their Contributions

Qalamuna
Ulama play a crucial role as agents of social control through their knowledge and leadership in society. In the Mandailing region, the presence of Ulama is significant and has contributed meaningfully to the development of Islamic scholarship in the ...
Muhammad Ikbal, Suryadi Nasution, Rahmi Seri Hanida   +2 more
doaj   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

Inovasi Blended Learning Dalam Pembelajaran Bahasa Arab: Tantangan dan Peluang di Era Society 5.0

Lisanuna: Jurnal Ilmu Bahasa Arab dan Pembelajarannya
Innovation in the field of education has become increasingly important in the era of Society 5.0, where smart technologies such as AI, Internet of Things (IoT), and big data are integral parts of everyday life. Arabic language learning must also adapt by
Samsuar Arani, Hidayatil Muslimah, Zikriati Zikriati, Danil Zulhendra   +3 more
doaj   +1 more source

On the Influence of Electric Polarisation Upon the Stainability of Nerve.

, 1929
Kunio Sato
openalex   +2 more sources

A STUDY OF EXPERIMENTAL NON-HEMOLYTIC STREPTOCOCCUS LESIONS IN VITALLY STAINED RABBITS [PDF]

, 1916
Russell L. Cecil
openalex   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Decrypting cancer's spatial code: from single cells to tissue niches

Molecular Oncology, EarlyView.
Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik, Shi Pan, Eloise Withnell, Hou Wang Lam, Maria Secrier   +4 more
wiley   +1 more source

The Cytology of Pseudomonas spp. as Revealed by a Silver-Plating Staining Method

, 1958
M. E. RHODES
openalex   +1 more source

The photoelectric measurement of coal dust stains on filter paper [PDF]

, 1951
C. N. Davies, Mary Aylward
openalex   +1 more source