Results 151 to 160 of about 2,042,513 (399)
Journal of Clinical Microbiology, 1991 R. Nugent, M. Krohn, S. Hillier
semanticscholar +1 more source
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Kontribusi Motivasi Kerja Dan Pengetahuan Pengelolaan Kelas Terhadap Kinerja Dosen Stain Padangsidimpuan [PDF]
, 2012 Penelitian ini bertujuan untuk mengetahui: (1) Motivasi kerja dosen STAIN Padangsidimpuan. (2) Pengetahuan pengelolaan kelas dosen STAIN Padangsidimpuan. (3) Kinerja dosen di STAIN Padangsidimpuan.
Ratonggi, Ratonggi
core
A New Staining Technic for Vaginal Smears in the Study of Exfoliative Cytology [PDF]
, 1950 Isadore Cohen, I. Jacques Yetwin
openalex +1 more source
Effect of chemotherapy on passenger mutations in metastatic colorectal cancer
Molecular Oncology, EarlyView.Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui +6 more
wiley +1 more source
The Optimization of Eluent Chromatography Thin Layer 2-D for The Purification of Isolat Alkaloid of Pulai Having Potention as Anti-Toxoplasma [PDF]
, 2015 There was a research having purpose to get pure alkaloid from pulai leaf in a way of chromatography thin layer two dimensions using 2 variants of eluent KLT 2-D.
Fauziyah, Begum +2 more
core
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source