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RandStainNA: Learning Stain-Agnostic Features from Histology Slides by Bridging Stain Augmentation and Normalization

International Conference on Medical Image Computing and Computer-Assisted Intervention, 2022
Stain variations often decrease the generalization ability of deep learning based approaches in digital histopathology analysis. Two separate proposals, namely stain normalization (SN) and stain augmentation (SA), have been spotlighted to reduce the ...
Yiqing Shen   +3 more
semanticscholar   +1 more source

Cell Staining

Cold Spring Harbor Protocols, 2022
When labeled antibodies are used to detect antigens in cells or tissues, several characteristics of an antigen can be readily determined. Most importantly, cell staining will show both the presence and subcellular localization of an antigen. Double-labeling techniques permit the simultaneous detection of two antigens, allowing comparisons of the ...
openaire   +2 more sources

Generative Adversarial Networks for Facilitating Stain-Independent Supervised and Unsupervised Segmentation: A Study on Kidney Histology

IEEE Transactions on Medical Imaging, 2019
A major challenge in the field of segmentation in digital pathology is given by the high effort for manual data annotations in combination with many sources introducing variability in the image domain.
M. Gadermayr   +5 more
semanticscholar   +1 more source

Differential Staining of Bacteria: Flagella Stain

Current Protocols in Microbiology, 2009
AbstractBacterial flagella are appendages used for motility. Their presence is a useful tool for identification and differentiation of prokaryotes. Since flagella are too thin to be seen by compound light microscopy, staining methods employ the use of a mordant (often tannic acid) to make them thick enough to see using an oil immersion objective.
Donald P, Breakwell   +2 more
openaire   +2 more sources

Differential Staining of Bacteria: Endospore Stain

Current Protocols in Microbiology, 2009
AbstractEndospore production is a very important characteristic of some bacteria, allowing them to resist adverse environmental conditions such as desiccation, chemical exposure, extreme heat, radiation, etc. The identification of endospores is also very important for the clinical microbiologist who is analyzing a patient's body fluid or tissue—there ...
Jackie, Reynolds   +2 more
openaire   +2 more sources

Cytochemical Staining

2017
Historically, the diagnosis and classification of acute leukemia involved morphologic review of blasts in the peripheral blood and bone marrow smears and cytochemical staining. Cytochemical stains, which are enzymatic colorimetric reactions that occur in the cells of interest, were necessary to assign and confirm myeloid and lymphoid lineage.
Michele E, Paessler   +2 more
openaire   +2 more sources

Preliminary Staining of Bacteria: Simple Stains

Current Protocols in Microbiology, 2009
AbstractSimple staining involves directly staining the bacterial cell with a positively charged dye in order to see bacterial detail, in contrast to negative staining where the bacteria remain unstained against a dark background. Curr. Protoc. Microbiol. 15:A.3E.1‐A.3E.5. © 2009 by John Wiley & Sons, Inc.
Rita B, Moyes   +2 more
openaire   +2 more sources

Staining Yeast

Cold Spring Harbor Protocols, 2006
INTRODUCTIONStaining yeast cells for the presence and localization of antigens has been particularly challenging because of several factors. The yeast cells are small, making the resolution of any antigen difficult; they have a thick cell wall that antibodies cannot penetrate and that is difficult to remove; and they grow in suspension, making handling
Ed, Harlow, David, Lane
openaire   +2 more sources

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