Results 61 to 70 of about 96,524 (260)

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

FEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani, Konstantinos Spanopoulos, Zoi Piperigkou, Nikos K. Karamanos   +3 more
wiley   +1 more source

Discrete Element Method for Simulation and Calibration of Cotton Stalk Contact Parameters

BioResources, 2022
To improve the accuracy of the discrete element research, physical and simulation experiments were used to calibrate the cotton stalk contact parameters. Based on the stalk-stalk and stalk-steel contact mechanics, the parameters were measured in physical
Jiali Li, Yongtao Lu, Xiangbin Peng, Peng Jiang, Bingcheng Zhang, Lanyu Zhang, Hewei Meng, Za Kan, Xinzhong Wang   +8 more
doaj   +2 more sources

Low irradiance alters carbon metabolism and delays flower stalk development in two orchids

, 2013
In Phalaenopsis, lowering irradiance has been used to delay flower stalk development but the accompanying biochemical changes remain poorly understood. We cultured two commercial Phalaenopsis-type orchids, Phalaenopsis cv.
P. P. Yang, C. C. Chen, P. H. Wu, W. H. Chen, K. M. Tseng, C. H. Liu, Y. C. Liu, H. L. Wang, Y. X. Huang   +8 more
core   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Effects of partial silage replacement with corn stover pellets on the rumen microbiota and serum metabolome of breeding cows

Frontiers in Microbiology
IntroductionStraw pellet ration replacing part of silage is of great significance for farmers to save farming costs and solve the lack of feed resources.
Chenyue Jiao, Changze Cui, Youpeng Qi, Meixian Zhang, Pengcheng Zhao, Shaopeng Chen, Xiangyan Wang, Jiang Hu, Jiang Hu, Bingang Shi, Bingang Shi, Ting Liu, Ting Liu, Zhidong Zhao, Zhidong Zhao, Fangfang Zhao, Fangfang Zhao   +16 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

The application of spectroscopic methods to predict sugarcane quality based on stalk cross-sectional scanning [PDF]

, 2012
With the increasing adoption of Precision Agriculture (PA) technique in the sugarcane industry, there is a growing need for a reliable method of in-field quality measurement.
Jensen, Troy, Nawi, Nazmi Mat, Chen, Guangnan   +2 more
core   +1 more source

Development of new measurement methods to determine sugarcane quality from stalk samples [PDF]

, 2014
Recently, there has been a growing interest within the Australian sugarcane industry to measure sugarcane quality in the field to further improve product quality and value.
Nawi, Nazmi Mat
core