Gαi1/3 Is a Novel Regulatory Target for RANKL Signal Transduction and Osteoporosis
ABSTRACT Osteoporosis, characterized by progressive bone loss and increased fracture risk, is a growing concern as the population ages. Current treatments, though advanced, remain limited, underscoring the necessity for novel therapeutic targets. Recent studies have shown that the immune system plays a key role in osteoporosis, with osteoclasts driving
Chaowen Bai +15 more
wiley +1 more source
Assessing the role of genotype by environment interaction as determinants of maize grain yield and lodging resistance. [PDF]
Yue H +7 more
europepmc +1 more source
RUNX2 Activation in Fibro/Adipogenic Progenitors Promotes Muscle Fibrosis in Muscular Dystrophy
This study revealed a novel role of the chemokine‐TGF‐β1‐RUNX2 axis in determining the fate of FAP differentiation and modulating muscle fibrosis in patients and mice with muscular dystrophies. ABSTRACT Clinical evidence indicates concurrent muscle inflammation and fibrosis in muscular dystrophies (MDs); however, the molecular mechanisms underlying ...
Pengkai Wu +12 more
wiley +1 more source
Metabolomic Variation in Sugarcane Maturation Under a Temperate Climate. [PDF]
Date Y, Ishikawa C, Ono H.
europepmc +1 more source
We present a dual‐organ, biomarker‐integrated ovaryendometrium organ‐on‐a‐chip that recapitulates 3D tissue complexity, menstrual cycle dynamics, and hormonal crosstalk. This platform enables real‐time, cell‐typespecific fluorescent readouts of reproductive toxicity using ANGPTL4 and SERPINB2 as early‐response reporters.
Soo‐Rim Kim +6 more
wiley +1 more source
Intercropping of short- and tall-stature maize decreases lodging risk without yield penalty at high planting density. [PDF]
Ren J +11 more
europepmc +1 more source
Effects of nitrogen fertilizer application rate on lodging resistance for rice (Oryza sativa L.) stem. [PDF]
Lu Y +8 more
europepmc +1 more source
Comparative transcriptome analysis reveals potential regulatory genes involved in the development and strength formation of maize stalks. [PDF]
Cheng S +8 more
europepmc +1 more source

