Results 111 to 120 of about 2,228,454 (224)

Cell‐Selective Delivery of RIBOTACs via an Anti‐EGFR Nanobody for Pancreatic Cancer Treatment

Advanced Science, EarlyView.
This study introduces an innovative strategy for the tumor‐selective catalytic degradation of oncogenic non‐coding RNA by interfacing a ribonuclease‐recruiting small molecule (RIBOTAC) with an EGFR‐targeting nanobody via a CTSB (Cathepsin B)‐responsive linker.
Tianli Luo, Yijuan Wang, Dengwang Chen, Yinghan Zhang, Yi Shuai, Hualiang Yao, Tao Jiang, Hang Jiang, Ming Zhong, Xiangeng Wang, Ziwei Wang, Chenchen Xu, Ajay Goel, Hoi Tang MA, Feng Gao, Xin Wang   +15 more
wiley   +1 more source

An Artificially Selected Cytokinin‐Pathway Transcription Factor Balances Soybean Yield and Pathogen Resistance

Advanced Science, EarlyView.
A cytokinin pathway transcription factor, RR2b, was artificially selected during soybean domestication and improvement based on its differential transcriptional activity, which correlates with ATT repeat polymorphisms in its promoter. RR2b balances yield and defense by fine‐tuning its expression level and offers a promising target for decoupling trade ...
Qun Ma, Yaqing Chen, Yiwen Gao, Xueting Hu, Qun Yang, Yucheng Liu, Peiyong Xin, Jijun Yan, Jinfang Chu, Lei Li, Zhixi Tian, Bo Ren   +11 more
wiley   +1 more source

Quantitative Genetic Analysis of Stalk Quality Characteristics in a Corn Synthetic [PDF]

, 1988
Considerable progress has been made in improving the standability of corn (tea mays L.). Further improvement of stalk lodging resistance is still necessary because of increased plant populations and fertilizer inputs.
Held, Maria Magdalena
core   +1 more source

Women of AHLAF: Focus on Diversity, Equity, and Inclusion

, 2021
Lodging Magazine sat down with American Hotel & Lodging Association Foundation Diversity & Inclusion Committee members to learn more about their passion, focus, and goals surrounding the task force.
Lodging Magazine
core  

Wearable Electro‐Thermal Haptic Stimulator Driven by a Self‐Powered Tactile Sensor for Realistic Stimulus Replication

Advanced Science, EarlyView.
We present a stimulus‐replicating system combining a tactile sensor with a wearable Peltier thermotactile module and concentric electrotactile electrode. Signals encoding pressure and temperature drive the stimulators to reproduce mechano‐thermal cues on the skin. AlN/PDMS encapsulation and SA/LA PSA ensure mechanical compliance and thermal efficiency.
Ey‐In Lee, Chae‐Young Kang, Kyuhyun Hwang, Jongbaeg Kim, Jin‐Woo Park   +4 more
wiley   +1 more source

QRICH1 Disrupts Endoplasmic Reticulum Homeostasis and Amplifies NF‐κB Signaling in Periodontal Ligament Stem Cells to Exacerbate Diabetic Periodontitis

Advanced Science, EarlyView.
QRICH1 has been established as a key factor contributing to impaired osteogenic potential and accelerated apoptosis of PDLSCs in diabetic periodontitis. QRICH1 not only significantly enhances UPR‐associated apoptotic signaling but also amplifies NF‐κB‐mediated inflammatory responses. Its inhibition restores osteogenic capacity and reduces alveolar bone
Han Li, Xiaoyu Yang, He Wang, Yunchun Kuang, Yiyao Hu, Houxuan Li, Shuhong Li, Deping Zeng, Jie Li, Jinlin Song   +9 more
wiley   +1 more source

Effect of Ethephon on Sensitivity Difference of Lodging Resistance in Different Maize Inbred Lines

Agronomy
Lodging imposes substantial constraints on maize yield potential and agronomic efficiency, critically undermining productivity and resource optimization in cultivation systems. This study aimed to elucidate the mechanism whereby ethephon enhances lodging
Siyao Liu, Feng Guo, Mengzhu Chai, Shiwei Gu, Dacheng Wang, Zihao Wang, Yidan Chen, Tenglong Xie, Deguang Yang, Qian Zhang   +9 more
doaj   +1 more source

SOX5 Orchestrates Malignant Evolution via Promoter‐Centric Chromatin Remodeling in MYC‐Driven B‐Cell Lymphoma

Advanced Science, EarlyView.
In MYC‐enforced B‐cell lymphoma, SOX5 occupies promoter‐proximal regulatory regions and is associated with reduced chromatin accessibility at the PCNP locus. PCNP repression promotes proliferative remodeling by limiting apoptosis and cell‐cycle restraint.
Yiyou Mao, Zhenyuan Jia, Xiao‐Qin Mu, Ruilin Wang, Jianli Ma, Qingyuan Zhang, Yuwei Deng   +6 more
wiley   +1 more source

Stalk lodging in popcorn and related plant characteristics as influenced by two hybrids and treatment with ethephon

, 1987
Stalk lodging of popcorn (Zea mays everta L.) causes considerable economic losses. Use of ethephon (2-chloroethyl phosphonic acid) as an antilodging agent in small grains is well documented.
Baltenberger, Deborah Cay Colville
core   +1 more source

Transcriptome and co-expression network analysis reveal the genetic basis of cell wall components in maize stalks

BMC Genomics
Cellulose (CEL), hemicellulose (HCE), and lignin (LIG) are crucial constituents of the cell wall in maize stalks, significantly influencing stalk resistance to lodging and external stresses.
Yao He, Zhike Deng, Shijiang He, Zhaojie Qi, Hengshuo Chang, Peng Liu, Zhong Chen, Chaoying Zou, Yaou Shen, Langlang Ma   +9 more
doaj   +1 more source