Results 161 to 170 of about 4,639 (250)

GCN2 in proteostasis: structural logic, signalling networks and disease

The FEBS Journal, EarlyView.
Threats to protein synthesis activate the kinase GCN2, initiating the integrated stress response (ISR). GCN2 is triggered by stalled ribosomes and uncharged tRNAs, which accumulate when amino acids are scarce. The ISR adjusts cellular physiology by promoting redox balance, protein quality control, and mitochondrial optimisation.
JiaYi Zhu, Stefan J. Marciniak
wiley   +1 more source

Management of Poor Treatment Adherence in Teenage-Onset Bipolar I Disorder Using Long-Acting Injectable Second-Generation Antipsychotics: A Case Report. [PDF]

Cureus
Raghavendra Prasad S, S N.
europepmc   +1 more source

Long‐read sequencing‐based atlas of tissue‐specific expression of DNM1L transcript variants

The FEBS Journal, EarlyView.
Targeted long‐read sequencing resolves full‐length DNM1L (Drp1) isoforms and reveals conserved, tissue‐specific expression patterns across human and mouse tissues. Functional assays show that Drp1 isoforms differ in their ability to drive mitochondrial fission, independent of abundance, with specific exons modulating activity.
Feng Yan, Jafar S. Jabbari, Naomi X. L. Ling, Anne M. Kong, Jia Q. Truong, Marnie L. Maddock, Ayeshah A. Rosdah, Christopher G. Langendorf, Lifang Zhang, Jarmon G. Lees, Sebastian Bass‐Stringer, Danise Ann Onda, Alice Pébay, Mirella Dottori, Kim Loh, Jessica K. Holien, Sean Lal, Nadia M. Davidson, Jonathan S. Oakhill, Shiang Y. Lim   +19 more
wiley   +1 more source

Editorial: Exploring digital mental health solutions for domestic violence victims in the post-pandemic era. [PDF]

Front Public Health
Su Z, Tong C, Bennett B, El-Hage W, McDonnell D, da Veiga CP, Xiang YT.   +6 more
europepmc   +1 more source

PERIODIZING GEOLOGICALLY OUTWITH (AND WITHOUT?) THE ANTHROPOCENE: PASTS, AGENCIES, AND THE TERRESTRIAL

History and Theory, EarlyView.
ABSTRACT As a periodization that is generally understood to refer to an era of Terrestrial relationships that developed with modernization and nuclearization, the Anthropocene cannot be applied simply to premodern histories and texts. However, it has introduced historians to geological periodization as a mode of describing periods of changed ...
Gwenffrewi J. Morgan
wiley   +1 more source

Technology-facilitated sexual violence against women and its health impact: a mixed-methods systematic review. [PDF]

BMC Public Health
Benítez-Hidalgo V, Pastor-Moreno G, Ruiz-Pérez I, Amaya-Santos S.   +3 more
europepmc   +1 more source

Taxonomic and functional patterns of arthropod succession after glacier retreat in the Dolomite Alps

Insect Conservation and Diversity, EarlyView.
Arthropod succession after glacier retreat varied among species and forelands in the Dolomites Alps, with community composition shaped by glacier identity, time since deglaciation and local environmental conditions. Functional composition shifted from small, highly dispersive pioneer species to larger, less dispersive taxa, reflecting increasing ...
Ivan Petri, Andrea Simoncini, Isabel Cantera, Barbara Valle, Marta Tognetti, Michael Bernasconi, Marina Serena Borgatti, Simone Giachello, Lisa Angelini, Gentile Francesco Ficetola, Silvio Marta, Paolo Pantini, Marco Caccianiga, Mauro Gobbi   +13 more
wiley   +1 more source

Bret/BRAT

Critical Quarterly, EarlyView.
Nicholas Smart
wiley   +1 more source

The gendered impact of time on inclusion in African organizations: A systematic literature review

International Journal of Management Reviews, EarlyView.
Abstract Management and organization research has paid limited attention to how gender, time and organizational dynamics intersect, particularly in shaping gender equality and inclusion. The extant literature also remains largely western‐centric in its focus on the conceptualizations of time and gendered time use.
Hakeem Adeniyi Ajonbadi, Olatunji David Adekoya, Chima Mordi, Toyin Ajibade Adisa, Oluwatimilehin Temitope Ologunoye   +4 more
wiley   +1 more source