Results 161 to 170 of about 59,594 (307)

Beyond the Outburst: Charting a New Frontier for Understanding and Treating Irritability in Autistic Adults

open access: yesAutism Research, EarlyView.
ABSTRACT Irritability is a prevalent and impairing feature associated with autism, yet remains poorly understood, particularly in adults. Drawing heavily on insights translated from pediatric and transdiagnostic literatures, we propose that irritability in autistic individuals often reflects a psychophysiological stress or threat response, rooted in a ...
Hsiang‐Yuan Lin   +3 more
wiley   +1 more source

A phase 1 evaluation of inhaled oxytocin: Physiologically‐based pharmacokinetic model informed dosing of a novel heat‐stable oxytocin delivery system

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aim To develop and validate a physiologically‐based pharmacokinetic (PBPK) model enabling inhaled oxytocin dose selection for clinical evaluation. Subsequently, to conduct a phase 1 study investigating the pharmacokinetics and safety of selected doses of an optimized inhaled oxytocin product in healthy, non‐pregnant female participants.
Pete Lambert   +6 more
wiley   +1 more source

S. aureus colonization and clinical symptoms remain stable upon topical XZ.700 treatment: Results of a double‐blind randomized clinical trial in patients with mild to moderate atopic dermatitis

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aim Recovering dysbiosis may improve atopic dermatitis (AD) symptoms. XZ.700 is a recombinant chimeric endolysin that specifically targets Staphylococcus aureus and could be a new treatment option for patients with AD. The aim of this first‐in‐human study was to evaluate the safety, tolerability and efficacy of topical XZ.700 and explore the ...
Laura W. J. van der Meulen   +13 more
wiley   +1 more source

Mystery Shopper: Antibiotics for sale at flea markets in a Mexican urban area. [PDF]

open access: yesFarm Comunitarios
Morales Rojas ME   +3 more
europepmc   +1 more source

Emotional nourishment begets academic coping during the primary to secondary school transition

open access: yesBritish Educational Research Journal, EarlyView.
Abstract The transition from primary to secondary school is widely viewed as the most demanding in a child's educational journey. Despite a wealth of research on this transition, little is known about the children's ‘lived experience’ of it across different contexts.
Peter Wood   +2 more
wiley   +1 more source

Effect of a 2-h daily exit on milk quality, activities and outside behavior of lactating cows. [PDF]

open access: yesFront Vet Sci
Arango S   +7 more
europepmc   +1 more source

Unsteady airfoil stall and stall flutter

open access: yes, 1971
Unsteady airfoil stall characteristics using static data input for predicting stall flutter boundaries of space shuttle ...
Ericsson, L. E., Reding, J. P.
core  

Measuring what matters: Evaluating the impact of curriculum decolonisation initiatives in UK business schools

open access: yesBritish Educational Research Journal, EarlyView.
Abstract Curriculum decolonisation has become a prominent feature of equity agendas in UK higher education, yet there remains limited empirical and theoretical work on how such initiatives are evaluated, particularly within business schools. This paper presents one of the first multi‐institutional empirical studies examining how UK business schools ...
Sally Everett   +2 more
wiley   +1 more source

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