Results 31 to 40 of about 299,991 (289)
The effect of 3-dimensional blade on the turbine characteristics has been investigated experimentally by model testing under steady flow conditions and simulated numerically by quasi-steady analysis under sinusoidal flow conditions, in order to improve ...
Manabu TAKAO +3 more
doaj +1 more source
Computational research on the formation mechanism of double humps in pump–turbines
The hump formation mechanism has not been fully understood so far, mainly because of two difficulties in analysis. The first one is how to find the most important external characteristic factor inducing humps, and the other is how to avoid too many ...
Yong Liu, Dezhong Wang, Hongjuan Ran
doaj +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Thick airfoils are conventionally adopted in the blade root region of a wind turbine to ensure structural safety under extreme conditions, despite the resulting power loss.
Hyeon-Gi Moon +3 more
doaj +1 more source
Targeting p38α in cancer: challenges, opportunities, and emerging strategies
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley +1 more source
Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada +5 more
wiley +1 more source
A stalled fork stalls recombination
Homologous recombination does not rescue stalled replication forks during S phase, report Meister et al. on page 537. Rather they find that replication and recombination are separated in terms of when and where they occur. If inappropriate recombination does occur when replication is stalled, replication forks fall apart.Researchers have debated ...
openaire +2 more sources
Comparative study of subsynchronous rotating flow patterns in centrifugal compressors with vaneless diffusers [PDF]
A comparative experimental investigation of the unstable operating modes of a centrifugal compressor was made. Impeller and/or diffuser rotating stall was observed, depending on the flow conditions.
Frigne, P., Vandenbraembussche, R.
core +1 more source
Cutaneous Phosphorylated Alpha‐Synuclein in Lewy Body Dementia
ABSTRACT Objective To determine the test performance of cutaneous phosphorylated alpha‐synuclein (P‐SYN) in dementia with Lewy bodies (DLB), individuals with reduced Montreal Cognitive Assessment (MoCA) and healthy controls. Methods This is the first subgroup analysis of the Synuclein‐One study, a prospective, blinded study evaluating P‐SYN detection ...
Christopher H. Gibbons +31 more
wiley +1 more source
The stall aerodynamic model based on Kirchhoff’s theory of flow separation is widely used in the identification and modeling of stall aerodynamic parameters. However, it has two defects.
Lixin Wang +4 more
doaj +1 more source

