Results 81 to 90 of about 73,280 (245)
AI Designed Conformation Locking Peptides Target STING to Restore Diabetic Wound Healing
Advanced Science, EarlyView.A generative AI pipeline identifies SCP‐1, a conformation‐locking peptide that stabilizes inactive STING. Incorporated into a dual‐responsive hydrogel for localized, MMP‐9‐triggered release, SCP‐1 suppresses inflammation, promotes reparative macrophage polarization, and accelerates diabetic wound healing.
Xinyu Li +8 more
wiley +1 more source
Advanced Science, EarlyView.Hypoxia‐adaptive bioelectronics based on poly(3,4‐ethylenedioxythiophene):poly(styrene sulfonate) (PEDOT:PSS)/polydopamine (PDA)/enzyme biocomposites couple O2‐centric biosensing with embedded O2 therapy to address oxygen‐deficient chronic wounds. Local O2 provision restores enzyme‐based metabolite sensing, while catalase‐mediated oxygen generation and
Songrui Liu +16 more
wiley +1 more source
Scalable Crackle‐Lithography for Multifunctional Enclosed Plastic Nanofluidic Devices
Advanced Science, EarlyView.Crackle‐lithography enables scalable fabrication of enclosed plastic‐substrate‐based nanofluidic devices with interconnected nanochannels that enable molecular transport, optical interrogation, confined electroless copper deposition, and ionic memristive behavior.
Tirumala Rao Dumpala +8 more
wiley +1 more source
Pitching Airfoil Boundary Layer Investigations [PDF]
, 2006 The present paper describes an experiment performed in a transonic wind tunnel facility where a new test section has been developed especially for the investigation of the unsteady flow above oscillating airfoils under dynamic stall conditions.
Richter, Kai +4 more
core
Advanced Science, EarlyView.Under normal conditions, MACF1 interacts with Rab14 and facilitates KIF16B‐mediated FGFR vesicle trafficking along microtubules to the plasma membrane, thereby supporting BMSC differentiation. In contrast, chronic GC exposure suppresses MACF1 expression, disrupting this transport and causing intracellular FGFR retention, which blunts osteogenic ...
Peihong Su +14 more
wiley +1 more source
Physical analysis of the coherent motion during hysteretic static stall of Naca foil using proper orthogonal decomposition [PDF]
, 2009 At static stall of airfoil, an hysteretic behavior (corresponding to an abrupt loss of lift) has been observed leading to a partially detached flow (called state I, upper increasing angle branch) and massively separated flow (called state II, lower ...
Billard, Jean-Yves +2 more
core
Advanced Science, EarlyView.Condensates at synapses organize synaptic vesicles (SVs) and are crucial for efficient neurotransmitter release, yet how RNA contributes to this mesoscale architecture remains poorly understood. Here we uncover that RNA modulates synapsin–driven condensates.
Branislava Rankovic +21 more
wiley +1 more source
Observations of the Growth and Decay of Stall Cells during Stall and Surge in an Axial Compressor
International Journal of Rotating Machinery, 2017 This research investigated unsteady events such as stall inception, stall-cell development, and surge. Stall is characterized by a decrease in overall pressure rise and nonaxisymmetric throughflow.
Adam R. Hickman, Scott C. Morris
doaj +1 more source
Advanced Science, EarlyView.Human iPSC‐derived Fabry cardiomyocytes exhibited broad transcriptional dysregulation, apoptosis, mitochondrial dysfunction, impaired reactive oxygen species handling, altered contractility, and abnormal calcium transient decay, potentially mediated by phospholamban hyperphosphorylation.
Malte Juchem +24 more
wiley +1 more source
Stall Flutter Control of a Smart Blade Section Undergoing Asymmetric Limit Oscillations
Shock and Vibration, 2016 Stall flutter is an aeroelastic phenomenon resulting in unwanted oscillatory loads on the blade, such as wind turbine blade, helicopter rotor blade, and other flexible wing blades.
Nailu Li +4 more
doaj +1 more source