Results 31 to 40 of about 229 (213)

Translating whole‐genome doubling into precision medicine in cancer

open access: yesMolecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Comparison and Sensibility Analysis of Warning Parameters for Rotating Stall Detection in an Axial Compressor

open access: yesInternational Journal of Turbomachinery, Propulsion and Power, 2020
The present paper aims at evaluating the surveillance parameters used for early stall warning in axial compressors, and is based on unsteady pressure measurements at the casing of a single stage axial compressor.
Gabriel Margalida   +3 more
doaj   +1 more source

A Unified Framework for Compressor Stall Inception

open access: yesVolume 10: Turbomachinery — Axial Flow Fan & Compressor Aerodynamics; Axial Flow Turbine Aerodynamics
Abstract This paper presents a first-of-a-kind description of compressor rotating stall inception that explains the two different routes to stall reported in the literature over the past four decades. A low-order dynamic system model, an actuator disk analysis, is shown to capture these two transient, stall inception behaviors, namely
Grimshaw, Sam   +3 more
openaire   +2 more sources

PANoptosis in the pathogenesis of myelodysplastic syndromes

open access: yesMolecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla   +4 more
wiley   +1 more source

Simulation of Broadband Noise Sources of an Axial Fan under Rotating Stall Conditions

open access: yesAdvances in Mechanical Engineering, 2014
Study on the influence of rotating stall on the aerodynamic noise of axial fan has important value to warn of the occurrence of stall through monitoring the noise variations.
Lei Zhang, Rui Wang, Songling Wang
doaj   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

open access: yesAging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Current Status and Challenges in Data Collection for Aerospace Coatings Deposited by Plasma Spraying

open access: yesAdvanced Engineering Materials, EarlyView.
An innovative approach has been integrated into the GRENAT project to optimize plasma spraying and coating performance. Raw materials are accelerated and melted in the plasma generated by torches, creating coatings. Monitoring sensors collect process data which are combined with ex situ characterization data.
Lila Randriamananjara   +8 more
wiley   +1 more source

Characterization of dynamic stall of a wind turbine airfoil with a high Reynolds number [PDF]

open access: yesWind Energy Science
This study shows an extensive analysis of dynamic stall on wind turbine airfoils, preparing for the development of a reduced-order model applicable to thick airfoils (t/c>0.21) in the future.
H. R. Kim   +4 more
doaj   +2 more sources

Stall and leading-edge vortex in a centrifugal compressor with vaned diffuser

open access: yesNihon Kikai Gakkai ronbunshu, 2015
The experimental and CFD analysis were conducted to investigate the relationship between stall and leading-edge vortex (LEV) in a centrifugal compressor with vaned diffuser.
Nobumichi FUJISAWA   +2 more
doaj   +1 more source

An Electrowetting Pump

open access: yesAdvanced Functional Materials, EarlyView.
A tubular electrowetting pump moves alternating droplets through a millimeter‐wide channel in discrete, reversible steps, functioning as a fluidic stepper motor. With no moving parts and electrodes insulated from the liquid, it delivers silent, accurate flow. Flexibility allows the pump to be woven directly into textiles for wearable, medical, and soft‐
Robert Hennig, Herbert Shea
wiley   +1 more source

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