Results 181 to 190 of about 3,742,472 (237)

Real-time imaging of transcriptional feedback in nonsense-mediated mRNA decay. [PDF]

Sci Adv
Islam MD, Das T, Singer RH, Sato H.
europepmc   +1 more source

Hybrid Macrocyclic Peptides — Synthetic Strategies to Diversify and Cyclize Peptide Libraries in Phage Display Selections

Chemistry – A European Journal, EarlyView.
Hybrid macrocyclic peptides unite genetically encoded peptide libraries with the structural complexity of synthetic small molecules. This Review critically analyzes phage‐compatible cyclization and diversification chemistries, highlights emerging opportunities beyond traditional cysteine‐based approaches, and outlines how future advances may enable the
Titia Rixt Oppewal, Clemens Mayer
wiley   +1 more source

RATEX: A Scalable RNA-Based Platform for Logical and Multi-Layered Cellular Programming. [PDF]

Angew Chem Int Ed Engl
Goh H, Kang H, Kim C, Kim J.
europepmc   +1 more source

The Kinesin Speed Paradox Revisited: How Can Cargoes Move Faster Than Their Motors?

Cytoskeleton, EarlyView.
ABSTRACT Intracellular transport is essential for cellular organization and function. Kinesin‐1, the founding member of the kinesin superfamily, delivers a wide range of cargoes along microtubules. Since its discovery, extensive work has identified cargo–kinesin interactions and regulatory mechanisms.
Kanako Iwasaki, Yasushi Okada
wiley   +1 more source

Infection with Toxoplasma gondii diminishes constitutive and IFN-gamma-induced HLA gene expression in human-derived macrophages

, 2009
Lueder, Carsten Guenter Kurt, Stalling, P.   +1 more
core   +2 more sources

A toxic STING-SAMHD1 axis drives replication stress in progeria and cancer cells. [PDF]

Nucleic Acids Res
Teodoro-Castro B, de Faria RC, Shashkova EV, Malique A, Adolph MB, Silva LND, Gonzalo S.   +6 more
europepmc   +1 more source

Increased Insulin Action, Glucose Metabolism and Muscle Function in Supervillin‐Knockout and Supervillin‐Mutant Mice

Cytoskeleton, EarlyView.
ABSTRACT We here describe mouse models with complementary homozygous Svil mutations. In skeletal muscle, Svil‐Mut mice express the Svil‐encoded N‐terminus fused to the βgal‐neo gene‐trap tag and lack the highly conserved archvillin C‐terminus; Svil‐KO mice lack expression of all known Svil‐encoded proteins; and Svil‐LoxP mice contain loxP sites for ...
Tara C. Smith, Lauren A. Tauer, Randall H. Friedline, Xiaodi Hu, Duy Tran, Yangyi E. Luo, Nacima Hadjout‐Rabi, Elisabeth R. Barton, Jason K. Kim, Elizabeth J. Luna   +9 more
wiley   +1 more source

New Insights Into the Three‐Dimensional Mechanics of the Flagellar Beat Cycle

Cytoskeleton, EarlyView.
ABSTRACT Advances in imaging at the molecular scale have provided greater detail concerning the three‐dimensional structure of the ciliary/flagellar axoneme. Additionally, it has recently been confirmed that electrostatic forces regulate the dynein‐tubulin interaction at the microtubule binding domain (MTBD) of dynein, and at the junction of the nexin ...
Charles B. Lindemann
wiley   +1 more source

Cell-body curvature reduces stall frequency to enhance Vibrio cholerae swimming and chemotaxis through hydrogels. [PDF]

Commun Biol
Malik M, Chen Z, Pyo AGT, Gitai Z, Wingreen NS, Grognot M.   +5 more
europepmc   +1 more source