Results 21 to 30 of about 3,742,472 (237)

The Relationship Between Austrian Tax Auditors and Self-Employed Taxpayers: Evidence From a Qualitative Study

open access: yesFrontiers in Psychology, 2019
A constructive, highly professional relationship between tax authorities and taxpayers is essential for tax compliance. The aim of the present paper was to explore systematically the determinants of this relationship and related tax compliance behaviors ...
Katharina Gangl   +4 more
doaj   +1 more source

Novel Traveling Wave Sandwich Piezoelectric Transducer with Single Phase Drive: Theoretical Modeling, Experimental Validation, and Application Investigation

open access: yesChinese Journal of Mechanical Engineering, 2021
Most of traditional traveling wave piezoelectric transducers are driven by two phase different excitation signals, leading to a complex control system and seriously limiting their applications in industry. To overcome these issues, a novel traveling wave
Liang Wang   +4 more
doaj   +1 more source

Myrmecophilus gallicus STALLING 2017

open access: yes, 2023
MYRMECOPHILUS GALLICUS STALLING, 2017 Three ♀♀, three nymphs, France: Aubagne, Camping du Garlaban (43.297°N 5.536°E, 146 m), 11. V.2015, leg. T. Szentiványi (HNHM).
Chobanov, Dragan   +9 more
core   +1 more source

Application of the singular spectrum analysis technique to study the recent hiatus on the global surface temperature record. [PDF]

open access: yesPLoS ONE, 2014
Global surface temperature has been increasing since the beginning of the 20th century but with a highly variable warming rate, and the alternation of rapid warming periods with 'hiatus' decades is a constant throughout the series. The superimposition of
Diego Macias   +2 more
doaj   +1 more source

First record of the ant-loving cricket Myrmecophilus fuscus Stalling, 2013 (Orthoptera: Myrmecophilidae) in mainland Spain [PDF]

open access: yes, 2015
We present the first published records of Myrmecophilus fuscus Stalling, 2013 from the Spanish mainland. We observed the species at various localities in Catalonia and in the city of Madrid. Six ant species are known hosts for M. fuscus in mainland Spain:
Thomas Stalling   +5 more
core   +1 more source

Non-bulk-like solvent behavior in the ribosome exit tunnel.

open access: yesPLoS Computational Biology, 2010
As nascent proteins are synthesized by the ribosome, they depart via an exit tunnel running through the center of the large subunit. The exit tunnel likely plays an important part in various aspects of translation. Although water plays a key role in many
Del Lucent   +3 more
doaj   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

open access: yesFEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos   +9 more
wiley   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

open access: yesMolecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim   +7 more
wiley   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

ATZ‐1 promotes DNA replication efficiency to maintain normal meiotic function

open access: yesFEBS Open Bio, EarlyView.
Absence of ATZ‐1 interferes with meiotic DNA replication and cell cycle function via CHK‐1. This causes downstream defects associated with DNA damage and genomic integrity. Taken together, this study suggests that ATZ‐1 influences DNA replication efficiency and cell cycle function to maintain normal meiotic function.
Taylin E. Gourley   +5 more
wiley   +1 more source

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