Results 101 to 110 of about 45,154 (289)
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
An English–Arabic analysis of stance-taking in public health crisis communication
Cogent Arts & HumanitiesThis study investigates stance-taking in the World Health Organization’s (WHO) pandemic declaration speech delivered on March 11, 2020, and its officially translated Arabic version, with the aim of exploring how stance is employed and re-conveyed across ...
Sewar Al-Qudah +2 more
doaj +1 more source
Prosodic features of stances in conversation
Laboratory Phonology, 2019 Stance—attitudes and opinions about the topic of discussion—has been investigated textually in conversation analysis, discourse analysis, and computational models, but little attention has focused on its acoustic-phonetic properties.
Valerie Freeman
doaj +2 more sources
Lying as a Parallax Stance [PDF]
, 2017 In this paper, an attempt is made to look at the phenomenon of lying from a dynamic perspective. First a few classic definitions of lying are considered and found to be inadequate due to the methodological assumption characteristic of the static style
Морозова, Е.И.
core
Dialogue as Data in Learning Analytics for Productive Educational Dialogue [PDF]
, 2015 This paper provides a novel, conceptually driven stance on the state of the contemporary analytic challenges faced in the treatment of dialogue as a form of data across on- and offline sites of learning.
Knight, Simon, Littleton, Karen
core +2 more sources
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Stance taking and Engagement in arbitration theories in the family court: An inquiry in judicial discourse analysis [PDF]
نشریه پژوهشهای زبانشناسیThe present study examines and describes the process of stance-taking and engagement in the arbitration theories related to the family court grounded on Hyland’s (2008) approach to voice and stance-taking.
Parisa Najafi +3 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Interpersonal stance in police interviews: content analysis [PDF]
, 2013 A serious game for learning the social skills required for effective police interviewing is a challenging idea. Building artificial conversational characters that play the role of a suspect in a police interrogation game requires computational models of ...
Akker, Rieks op den +3 more
core +2 more sources
Self-dual Einstein Spaces, Heavenly Metrics and Twistors
, 2010 Four-dimensional quaternion-Kahler metrics, or equivalently self-dual Einstein spaces M, are known to be encoded locally into one real function h subject to Przanowski's Heavenly equation.
Boris Pioline +7 more
core +3 more sources