Results 121 to 130 of about 45,154 (289)
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Disciplinary enculturation and authorial stance
Achieving a credible and authoritative stance in academic writing requires a writer’s disciplinary enculturation. While postgraduate students may have a foot in the door, expert writers have accumulated much knowledge and practice in their research ...
Xuyan Qiu, Xiaohao Ma
doaj
Enkinaesthetic polyphony: the underpinning for first-order languaging [PDF]
We contest two claims: (1) that language, understood as the processing of abstract symbolic forms, is an instrument of cognition and rational thought, and (2) that conventional notions of turn-taking, exchange structure, and move analysis, are ...
Stuart, Susan A.J., Thibault, Paul J.
core
STANCE TAKING IN THE SERMON, "THE POWER OF DEDICATION"
Bishop Adelakun’s messages are sites for posturing Christianity in Nigeria and the need to live a pleasing life to God. Existing linguistic and nonlinguistic studies on religious discourses, especially from the Christendom focused mostly on clergymen like Pastor Enoch Adeboye, Bishop Oyedepo, Pastor Paul Enenche and others, with little attention paid ...
openaire +1 more source
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Strategic use of stance-taking devices in English language academic texts is a key indicator of the proficiency of any academic writer. While this is true of first language (L1) and second language (L2, ESL or EFL) writers alike, developing the ability ...
Muhammad Afzaal +5 more
doaj +1 more source
Stance: позиція суб’єкта дискурсивної діяльності [PDF]
У статті здійснюється спроба уяснити, яким чином комунікант позиціонує себе у дискурсі. Береться до уваги ситуативно зумовлена, прагматична та інтеракційна природа позиціонування, розглядаються його різновиди.
Морозова, О.І.
core
The role of disciplinary enculturation in stance-taking in L2 academic writing
Stance-taking in academic writing reflects the cognitive and metacognitive processes underlying persuasion. However, most existing studies have either examined L2 writers at a single academic level or in genres other than MA theses and PhD dissertations or focused predominantly on East Asian contexts. To address this gap, this corpus-based study traces
Berker, Kurt, Hüseyin, Kafes
openaire +2 more sources

