Results 131 to 140 of about 45,154 (289)
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Humanities & Social Sciences CommunicationsDrawing on the key notions of style/styling and stance as positioning practices, this article analyzes the styling practices of fraudsters in institutional impersonation fraud (IIF), namely, how fraudsters style themselves and others (i.e., targets and ...
Mengna Liu, Xiqiao Liang, Jinshi Chen
doaj +1 more source
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Pronouns as stance markers in the Coruña Corpus : an analysis of the CETA, CEPhiT and CHET. [PDF]
, 2017 [Abstract] It is now widely accepted that knowledge is negotiated and negotiation implies involvement on the part of both readers and writers. Since there seems to be some connection between involvement and stancetaking (Freeman et al. 2014: 1), it seems
Moskowich, Isabel
core +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Masculinity in lesbian discourse: the case of butch and femme [PDF]
, 2015 This chapter explores the ways in which a lesbian community of practice perform a ‘butch’ identity. It uses discourse analysis to consider an interaction between them, showing a shared sense of self to be produced which rejects traditional symbols of ...
Jones, Lucy
core
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Talking About Drug Use: Positioning and Reflexivity in Drug Research Interviews and Beyond
Forum: Qualitative Social Research, 2014 The recognition of the role of discourse in the production of self-understandings and subjectivity has undergone considerable theoretical development over the past decades.
Per Kristian Hilden
doaj
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source