Results 81 to 90 of about 45,154 (289)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Maximal entanglement from quantum random walks

open access: yes, 2011
The conditions under which entanglement becomes maximal are sought in the general one--dimensional quantum random walk with two walkers. Moreover, a one--dimensional shift operator for the two walkers is introduced and its performance in generating ...
Alles, B., Gunduc, S., Gunduc, Y.
core   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

English 4210—Syllabus [PDF]

open access: yes, 2015
The syllabus for 4210 English: Writing for Social Justice. The syllabus includes an introduction and course overview, learning objectives, competencies, course assignments, evaluation, resources, and class ...
Godbee, Beth
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

How did the discussion go: Discourse act classification in social media conversations

open access: yes, 2018
We propose a novel attention based hierarchical LSTM model to classify discourse act sequences in social media conversations, aimed at mining data from online discussion using textual meanings beyond sentence level. The very uniqueness of the task is the
B O’Connor   +10 more
core   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Educação para sentido na vida e valores: percepção de universitários a partir do livro “Em busca de sentido”, de Viktor Frankl

open access: yesRevista Brasileira de Estudos Pedagógicos, 2019
Resumo: A sensação de vazio e falta de sentido na vida tem se disseminado na sociedade contemporânea, especialmente na juventude. Portanto, se faz necessária uma educação que promova o desenvolvimento pessoal ancorado no sentido de vida, que é ...
David Moises Barreto dos Santos
doaj   +1 more source

Between fact and norm : narrative and the constitutionalization of founding moments [PDF]

open access: yes, 2019
Both the subject who gives birth to a constitution and the time a constitution comes into being are part of the multifarious construct of the genesis of a constitution.
Kuo, Ming-Sung
core  

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

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