Results 141 to 150 of about 4,967,798 (324)
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Comfort-Centered Design of a Lightweight and Backdrivable Knee Exoskeleton
, 2019 This paper presents design principles for comfort-centered wearable robots and their application in a lightweight and backdrivable knee exoskeleton. The mitigation of discomfort is treated as mechanical design and control issues and three solutions are ...
Carriero, Alessandra +10 more
core
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Stance Detection in the Context of Fake News—A New Approach
Future InternetOnline social networks (OSNs) are inundated with an enormous daily influx of news shared by users worldwide. Information can originate from any OSN user and quickly spread, making the task of fact-checking news both time-consuming and resource-intensive.
Izzat Alsmadi +3 more
doaj +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
BERTtoCNN: Similarity-preserving enhanced knowledge distillation for stance detection. [PDF]
PLoS One, 2021 Li Y, Sun Y, Zhu N.
europepmc +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Stance detection with BERT embeddings for credibility analysis of information on social media. [PDF]
PeerJ Comput Sci, 2021 Karande H +4 more
europepmc +1 more source
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Stance detection in Arabic with a multi-dialectal cross-domain stance corpus
Social Network Analysis and MiningAbstract We present a cross-domain and multi-dialectal stance corpus for Arabic, covering the major dialect groups and four Arab regions. This research provides an important language resource for automating the task of stance detection in Dialectal Arabic while carefully considering the subtle differences in stance expression across various ...
Anis Charfi +5 more
openaire +1 more source