Results 101 to 110 of about 154,299 (301)

Multi-segment foot kinematics and plantar fascia strain during treadmill and overground running [PDF]

open access: yes, 2014
Although physiologically beneficial, running is known to be associated with a high incidence of chronic injuries. Excessive coronal and transverse plane motions of the foot segments and strain experienced by the plantar fascia are linked to the ...
Sinclair, Jonathan Kenneth   +2 more
core  

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

A new view of responses to first-time barefoot running. [PDF]

open access: yes, 2015
We examined acute alterations in gait and oxygen cost from shod-to-barefoot running in habitually-shod well-trained runners with no prior experience of running barefoot.
Andersen, Mikael Rørdam   +6 more
core   +3 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Discourse patterns of affective stance in paediatric online consultative encounters

open access: yesLanguage and Semiotic Studies
The paediatric online consultative forum, where putative patients interact with physicians, has become a lifesaver for many, especially during the COVID-19 lockdown era in Nigeria.
Opeyemi Olajimbiti Ezekiel   +1 more
doaj   +1 more source

What Can Quantitative Gait Analysis Tell Us about Dementia and Its Subtypes? A Structured Review [PDF]

open access: yes, 2017
Distinguishing dementia subtypes can be difficult due to similarities in clinical presentation. There is increasing interest in discrete gait characteristics as markers to aid diagnostic algorithms in dementia.
Galna, Brook   +5 more
core   +2 more sources

The Role of the Korean Topic Marker in Foregrounding Speaker Stance

open access: yesAnnual Meeting of the Berkeley Linguistics Society, 1991
Proceedings of the Seventeenth Annual Meeting of the Berkeley Linguistics Society: General Session and Parasession on The Grammar of Event Structure (1991), pp.
openaire   +2 more sources

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Head nouns as modal stance markers –academic texts vs. legal texts

open access: yesLidil, 2010
The aim of this paper is to substantiate on the one hand that head nouns are modal expressions allowing the writer to mark her stance in the text. On the other hand, it shows that the purpose and the social role of a text can be perceived in both its ...
Issa Kanté
doaj   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

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