Results 51 to 60 of about 237,005 (218)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
A Dynamic Modeling Approach: Simplifying DFIG Theory, Simulation, and Analysis
EnergiesThe operation and modelling of doubly fed induction generators (DFIGs) are quite different in grid-connected and stand-alone operated wind energy conversion systems (WECSs).
Mehmet Dal, Ralph M. Kennel
doaj +1 more source
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
IEEE Open Journal of Power ElectronicsThis article introduces a non-isolated three-port converter with a high voltage gain. The proposed converter employs a boosting technique that combines a switched capacitor and a coupling inductor, integrating both input ports into a single inductor ...
Sina Ahmadian +4 more
doaj +1 more source
Advances in Electrical and Computer Engineering, 2012 This paper presents the modeling and operational testing of an isolated permanent magnet synchronous generator (PMSG), driven by a small wind turbine with a battery energy storage system during wind speed and load variations.
BAROTE, L., MARINESCU, C.
doaj +1 more source
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Optimal planning of stand-alone microgrids incorporating reliability
Journal of Modern Power Systems and Clean Energy, 2014 This paper proposes a new method for the planning of stand-alone microgrids. By means of clustering techniques, possible operating scenarios are obtained considering the daily patterns of wind and load profiles.
Chengshan Wang +4 more
doaj +1 more source