Results 81 to 90 of about 1,286,748 (345)

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Research into the operating modes of a stand-alone dual-channel hybrid power system

AIMS Energy
The article describes the development and simulation of a stand-alone hybrid power system based on a variable-speed diesel generator and a hydrogen fuel cell generation system.
Andrey Dar'enkov , Aleksey Kralin, Evgeny Kryukov , Yaroslav Petukhov   +3 more
doaj   +1 more source

Feasibility Analysis and Simulation of a Stand-Alone Photovoltaic Energy System for Electricity Generation and Environmental Sustainability – equivalent to 650VA fuel-powered generator - popularly known as I pass my neighbour

Frontiers in Energy Research, 2015
Photovoltaic (PV) power system can be used to replace wholly 650VA generator for electricity generation for household use in Nigeria. This paper presented the feasibility analysis of load data and simulation study of a stand-alone PV power system that ...
Vincent Anayochukwu Ani
doaj   +1 more source

Control aspects of the Schuchuli Village stand-alone photovoltaic power system [PDF]

A photovoltaic power system in an Arizona Indian village was installed. The control subsystem of this photovoltaic power system was analyzed. The four major functions of the control subsystem are: (1) voltage regulation; (2) load management; (3) water ...
Culler, J. E., Delombard, R., Groumpos, P. P.   +2 more
core   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Exploiting wind-solar resource complementarity to reduce energy storage need

AIMS Energy, 2020
Resource complementarity carries significant benefit to the power grid due to its smoothing effect on variable renewable resource output. In this paper, we analyse literature data to understand the role of wind-solar complementarity in future energy ...
Solomon A. A., Michel Child , Upeksha Caldera, Christian Breyer   +3 more
doaj   +1 more source

Design and fabrication of a photovoltaic power system for the Papago Indian village of Schuchuli (Gunsight), Arizona [PDF]

A stand alone photovoltaic power system for installation in the Papago Indian village of Schuchuli is being designed and fabricated to provide electricity for village water pumping and basic domestic needs.
Bifano, W. J., Ice, W. J., Ratajczak, A. F.   +2 more
core   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source

Low-frequency switching voltage regulators for terrestrial photovoltaic systems [PDF]

The photovoltaic technology project and the stand alone applications project are discussed. Two types of low frequency switching type regulators were investigated.
Delombard, R.
core   +1 more source