Results 51 to 60 of about 4,043,334 (304)

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Biomass production and nitrogen balance of naturally afforested silver birch (Betula pendula Roth.) stand in Estonia

open access: yesSilva Fennica, 2016
Silver birch ( Roth.) is one of the main pioneer tree species occupying large areas of abandoned agricultural lands under natural succession in Estonia. We estimated aboveground biomass (AGB) dynamics during 17 growing seasons, and analysed soil nitrogen
Jürgen Aosaar   +6 more
doaj   +1 more source

Standing Rights and Regulatory Dynamics in the EU [PDF]

open access: yes, 2013
This contribution looks at the recent changes in locus standi (standing rights) for individual applicants from the perspective of judicial-regulatory dynamics. Article 263 TFEU significantly widens the standing rules for non-privileged applicants (i.e.
openaire   +2 more sources

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Forest dynamics [version 1; referees: 2 approved]

open access: yesF1000Research, 2016
Forest dynamics encompass changes in stand structure, species composition, and species interactions with disturbance and environment over a range of spatial and temporal scales.
Lee Frelich
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Heterogeneidad estructural y espacial de un bosque mixto dominado por Nothofagus dombeyi después de un disturbio parcial Structural and spatial heterogeneity of a mixed Nothofagus donibeyi-dominate forest stand after a partial disturbance

open access: yesRevista Chilena de Historia Natural, 2010
Los bosques dominados por Nothofagus dombeyi están entre las formaciones boscosas naturales más abundantes y productivas de la región templada de Sudamérica. En Chile son comunes los bosques secundarios dominados por N.
DANIEL P SOTO   +3 more
doaj  

STUDY ON MONGOLIAN FOREST STAND DYNAMICS USING MATHEMATICAL MODELING

open access: yesProceedings of the Mongolian Academy of Sciences, 2017
A Global warming, climate change and negative human activities are expected to directly and negatively influence Mongolia’s forest resource area and quality [21].
Khulan M, Liu Junchang
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

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