Results 141 to 150 of about 899,709 (306)

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

Forest floor vegetation in Sweden [PDF]

open access: yes, 2012
In boreal forests, dwarf-shrubs (Vaccinium spp.) often dominate the forest floor and are key-stone species in ecosystems due to their importance for nutrient cycling and as a major food source for herbivores. Forestry affects the vegetation both directly
Hedvall, Pär-Ola
core  

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Summer Annual Forage Mixtures Trial [PDF]

open access: yes, 2015
In 2015, the University of Vermont Extension Northwest Crops and Soils Program evaluated yield and quality of six summer annual forage species and five mixtures at Borderview Research Farm in Alburgh, VT.
Calderwood, Lily   +5 more
core   +1 more source

Interseeding Forage Kochia into Established CRP Grass Stands

open access: yes, 2016
This fact sheet is a summary of a research project that documented that interseeding forage kochia into existing CRP can increase its potential use for fall and winter grazing by livestock.
Banks, Jeffrey E.   +2 more
openaire   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Development of an early warning system of crop moisture conditions using passive microwave [PDF]

open access: yes
Emissivities were calculated from the Nimbus 5 electrically scanning microwave radiometer (ESMR) over 25 km grid cells for the southern Great Plains includin the western two-thirds of Kansas and Oklahoma and northwest Texas.
Harder, P. H., II, Mcfarland, M. J.
core   +1 more source

Taxpayer Standing and \u3cem\u3eDaimlerChrysler v. Cuno:\u3c/em\u3e Where Do We Go From Here? [PDF]

open access: yes, 2006
In granting certiorari in the case of Daimler-Chrysler Corp. v. Cuno, the Supreme Court asked the parties to brief whether respondents have standing to challenge Ohio\u27s investment tax credit.
Hickman, Kristin E., Tobin, Donald B.
core   +1 more source

STANDING COMMITTEE ON ETHICS ESTABLISHED BY BOARD [PDF]

open access: yesAnthropology News, 1969
David F Aberle, David M Schneider
openaire   +1 more source

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