Results 191 to 200 of about 899,709 (306)

Long-term recovery of canopy 3D structural diversity following wildfires in the world's largest temperate woodland. [PDF]

Proc Biol Sci
Zhang B, Prober SM, O'Donnell A, Gosper CR, Fischer F, Zdunic K, Jucker T.   +6 more
europepmc   +1 more source

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

Molecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande, Marcela de Oliveira Silva, Mariana Bisarro dos Reis, Rodrigo de Oliveira Cavagna, Luciane Sussuchi, Icaro Alves Pinto, Natalia Zampieri Pontes, Rodrigo Sampaio Chiarantano, Flavio Augusto Ferreira da Silva, Pedro de Marchi, Letícia Ferro Leal, Rui M. Reis   +11 more
wiley   +1 more source

Floristic assessment and soil-vegetation dynamics in an arid zone: a case study of the old Katameya-Ain Sokhna Road, Eastern Desert, Egypt. [PDF]

Sci Rep
Salama SG, Marie AH, Bedair R.
europepmc   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Spatial Distribution Patterns of Dominant Tree Species and Their Associations with Soil Factors in Subalpine Secondary Forests of Western Sichuan. [PDF]

Plants (Basel)
Zhao J, Liu X, Wang L, Feng Q, Gou C, Bai J, Yang X.   +6 more
europepmc   +1 more source

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

Molecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard, Cristina Mitric, Melanie Care, Tracy L. Stockley, Raymond H. Kim, Jeanna McCuaig, Blaise Clarke, Laura Ranich, Clare Sheen, Sarah E. Ferguson, Liat Hogen, Taymaa May, Marcus Q. Bernardini   +12 more
wiley   +1 more source

Functions, challenges and opportunities of health professions education units in Africa: a qualitative study across Eastern, Southern and Western regions. [PDF]

BMC Med Educ
Welch SB, Hansen A, Nawagi F, Singaram VS, Nelson GX, van Schalkwyk S, Doobay-Persaud AA, Hall ZZ, Kiguli-Malwadde E.   +8 more
europepmc   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Carbon stock, fluxes, and partitioning in Pinus taeda plantations are affected by genetic variation and stand density in Southeast Brazil. [PDF]

Carbon Balance Manag
Campoe OC, Cordeiro NG, Rojas G, Albaugh TJ, Cook RL, Rubilar RA, Carter DR, Alvares CA, Maier CA.   +8 more
europepmc   +1 more source

Putting the Cell Biology Establishment on the Stand [PDF]

Cell, 2002
openaire   +1 more source