Results 241 to 250 of about 1,521,543 (298)

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

open access: yesMolecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington   +10 more
wiley   +1 more source

Ultra-deep <i>vs</i>. standard swept-source optical coherence tomography for posterior vitreous detachment assessment: a retrospective comparative study. [PDF]

open access: yesQuant Imaging Med Surg
Lin Z   +14 more
europepmc   +1 more source

Performance of Vision-Enabled Large Language Models in Image-Based Electrocardiogram Interpretation: Exploratory Evaluation. [PDF]

open access: yesJ Med Internet Res
Soubh N   +7 more
europepmc   +1 more source

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