Density Adjusted Spectral Clustering Algorithm Based on Neighborhood Standard Deviation
工程科学与技术Objective Clustering involves partitioning given data into multiple classification clusters without requiring knowledge of the true labels. In other words, clustering is an unsupervised learning process that ensures that samples within the same cluster ...
Xiaoyu GUO +5 more
doaj
Standard Deviation Effect of Average Structure Descriptor on Grain Boundary Energy Prediction. [PDF]
Materials (Basel), 2023 Dang R, Yu W.
europepmc +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
The Residual Structure of Unfolded Proteins was Elucidated from the Standard Deviation of NMR Intensity Differences. [PDF]
Protein Pept Lett, 2023 Mizuno F +4 more
europepmc +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Importance of Pattern Standard Deviation of Humphrey 10-2 Visual Field to Evaluate Central Visual Function in Patients with Early-Stage Glaucoma. [PDF]
J Clin Med, 2023 Shin HJ, Oh SE, Park CK, Park HL.
europepmc +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
On the Effect of Standard Deviation of Cationic Radii on the Transition Temperature in Fluorite-Structured Entropy-Stabilized Oxides (F-ESO). [PDF]
Materials (Basel), 2023 Spiridigliozzi L +2 more
europepmc +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source