Results 131 to 140 of about 6,328,118 (260)

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Estimation of the standard deviation based on the mean absolute deviation

open access: yes, 2021
This thesis deals with the average absolute deviation and its use for the estimation of the standard deviation. First, the important notions are defined, in particular the mean absolute deviation and the average absolute deviation.
Lipavská, Kateřina
core  

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Average growth rate (± standard deviation) and grazing rates (± standard deviation) of Ochromonas sp. strain CCMP1393 in different treatments.

open access: yes, 2018
Average growth rate (± standard deviation) and grazing rates (± standard deviation) of Ochromonas sp. strain CCMP1393 in different treatments.
Zhenfeng Liu (431113)   +5 more
core   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Imbalanced Data Classification Based on Improved Random-SMOTE and Feature Standard Deviation

open access: yesMathematics
Oversampling techniques are widely used to rebalance imbalanced datasets. However, most of the oversampling methods may introduce noise and fuzzy boundaries for dataset classification, leading to the overfitting phenomenon.
Ying Zhang, Li Deng, Bo Wei
doaj   +1 more source

Standard deviation of line objects in geographic information science

open access: yes, 2014
Standard deviation of points is regarded as an effective precision indicator and has been used widely for over 100 years. However, to date, no standard deviation for line objects exists, despite lines being the most fundamental geometric objects in ...
Shi, W, You, Y, Shao, P, Wan, Y
core   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Standard deviation of all genes for biological and technical variance, showing median standard deviation, interquartile ranges and outliers.

open access: yes, 2013
Standard deviation of all genes for biological and technical variance, showing median standard deviation, interquartile ranges and outliers.
Roy Robins-Browne (150088)   +3 more
core   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

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