Results 161 to 170 of about 3,881,044 (260)

Engineering Morphological Anisotropy to Control the In Vivo Transport Dynamics, Clearance, and Biodistribution of Silica Nanocarriers

Advanced Science, EarlyView.
Morphological anisotropy directs the in vivo transport under physiological flow and clearance of silica nanocarriers. Increasing anisotropy reduces cellular uptake, suppresses hepatic and splenic sequestration, and prolongs systemic circulation by steering particles toward the central flow core.
Xiaofei Li, Yingjie Yu, Tianchang He, Xiaoyan Fang, Wenhua Yang, Luying Zhou, Hao Fan, Guimei Lin, Daniel Crespy, Katharina Landfester, Junfeng Zhang, Shuai Jiang   +11 more
wiley   +1 more source

Clinical Performance of an Isofocal Toric Intraocular Lens with Double C-Loop Haptics: A Multicenter Retrospective Study. [PDF]

Clin Ophthalmol
Daya S, Akahoshi T, Bosc C, Di Maria A, Espinosa Lagana M, Sasso N, Gaeta A.   +6 more
europepmc   +1 more source

OTUD6A‐Mediated Deubiquitination of PRDX1 Protects Against Oral Ulcer by Restoring Mitochondrial Function

Advanced Science, EarlyView.
In human oral keratinocytes, OTUD6A promoted cell migration by deubiquitinating and stabilizing PRDX1. Conversely, OTUD6A deficiency reduced PRDX1 stability, triggering mitochondrial dysfunction and aggravating OU progression. ABSTRACT Oral ulcers (OU), as the most highly prevalent and recurrent oral mucosal lesion, have an unclear pathogenesis that ...
Xiaoyu Sun, Ruiwei Jia, Xingbei Pan, Rui Huang, Jiahong Chen, Ziyi Yao, Lei Yin, Jun Ma, Hongjieliang Wang, Xinyu Huang, Yilin Ma, Yifan Ping, Yuanyuan Chen, Huining Wang, Shengbin Huang, Guang Liang   +15 more
wiley   +1 more source

Geometric Transformation Algorithm for Acetabular Cup Orientation: Converting 2D Radiographic Projections to 3D Spatial Positioning. [PDF]

In Vivo
Aktas G, Hensler L, Dippel S, Heins P, Mayor J, Clausen JD, Liodakis E, Sehmisch S, Pacha TO.   +8 more
europepmc   +1 more source

Computationally Evidence‐Grounded Sequence‐First Design of Peptide Binders

Advanced Science, EarlyView.
BOND‐PEP enables controllable, sequence‐first peptide binder design by grounding generation in binding evidence retrieved for each target. It uses topology‐conditioned message passing to integrate relevant peptide examples with the target protein sequence, forming a residue‐level representation that guides the generation of diverse, target‐specific ...
Wenze Ding
wiley   +1 more source

Effects of Unilateral Proximal-Thigh Blood Flow Restriction Added to Sit-to-Stand Training on Trunk Extensor Endurance and Posturographic Measures of Postural Steadiness in Healthy Young Adults: A Randomized Controlled Trial. [PDF]

J Clin Med
Güler MA, Ulaşkın E, Kurt İ, Yılmaz SN, Doğan E.   +4 more
europepmc   +1 more source

Pointwise ellipse constructions based on the affinity between the circle and the ellipse

, 2015
summary:Definition of affinity in a plane and its properties. Ellipse as an image of a circle in different types of affinity in a plane. The cross-piece construction of an ellipse and its relationship to the parallelogram method.
Králová, Alice
core  

Decoupling Fabrication From Encoding: DNA‐Addressable Template Microparticles for Large, User‐Defined Optical Barcode Libraries

Advanced Science, EarlyView.
A universal hydrogel microparticle template with five DNA‐addressable domains decouples particle fabrication from barcode writing. Contact‐free multilaminar flow lithography produces >106 templates/h, and post‐fabrication domain‐selective hybridization converts one batch into large, user‐defined optical barcode libraries with robust decoding and re ...
Akihiro Eguchi, Yuichiro Iwamoto, Hinata Tokuda, Haruka Narita, Adrian M. Martin, Sadao Ota   +5 more
wiley   +1 more source

Seismic evidence for lower-mantle heat supply beneath the Cordilleran slab window in western Canada. [PDF]

Nat Commun
Zhang Q, Audet P, Ji C, Estève C.
europepmc   +1 more source

Achieving High‐Instantaneous Pulse Power in Contact‐Separation TENG via Series Capacitive Voltage Control Architecture

Advanced Science, EarlyView.
Conventional contact‐separation triboelectric nanogenerators generate high voltage but deliver limited power due to premature charge dissipation. Here, a capacitive charge reservoir architecture decouples charge accumulation from discharge triggering, enabling sequential voltage amplification via floating‐layer capacitive coupling.
Ajay Haridas CP, Prosenjit Das, Kinsuk Naskar, Titash Mondal   +3 more
wiley   +1 more source