Addressing the estimation of standard errors in fixed effects meta-analysis. [PDF]
Domínguez Islas C, Rice KM.
europepmc +1 more source
Evolution‐guided yeast complementation reveals functional differences in human PSPH variants
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez +6 more
wiley +1 more source
Preparing for a meta-analysis of rates: extracting effect sizes and standard errors from studies of count outcomes with person-time denominators. [PDF]
Spittal M.
europepmc +1 more source
We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli +3 more
wiley +1 more source
Prevalence and determinants of caesarean section delivery in Ethiopia: analysis of the 2019 EMDHS using Poisson regression with robust standard errors. [PDF]
Wondmeneh TG.
europepmc +1 more source
Conditional Precision of Measurement for Test Scores: Are Conditional Standard Errors Sufficient? [PDF]
Nicewander WA.
europepmc +1 more source
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty +13 more
wiley +1 more source
Robust inverse probability weighted estimators for doubly truncated Cox regression with closed-form standard errors. [PDF]
Vazquez O, Xie SX.
europepmc +1 more source
Frequentist Standard Errors of Bayes Estimators. [PDF]
Lee D, Carroll RJ, Sinha S.
europepmc +1 more source
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen +5 more
wiley +1 more source

