Results 71 to 80 of about 3,594,858 (294)

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

The normative aspect of the Russian standard language in the methodology of Russian teaching as a foreign language

open access: yesPolylinguality and Transcultural Practices, 2013
The article is devoted to the actual problems of mastering the rules of professional language by foreign students. This article presents some typical steady mistakes that foreign students make, gives recommendations about their overcoming.
A B Nedosugova
doaj  

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

open access: yesMolecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson   +2 more
wiley   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

open access: yesMolecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj   +4 more
wiley   +1 more source

Preserving cultural heritage by teaching idioms to young learners as part of imaginative language in Setswana

open access: yesSouth African Journal of Childhood Education, 2016
Teachers need creative strategies and techniques when teaching idioms in Setswana. However, they do not know what idioms are nor are they aware that through idioms cultural heritage can be preserved and that idioms can be taught as part of imaginative ...
Refilwe Ramagoshi, Ina Joubert
doaj   +1 more source

Consolidated proposal for encoding the Old Hungarian script in the UCS [PDF]

open access: yes, 2012
This is a proposal to encode the Old Hungarian script in the international character encoding standard Unicode. The script was published in Unicode Standard version 8.0 in June 2015.
Everson, Michael, Szelp, André Szabolcs
core  

Comments on ``Lattice Formulation of the Standard Model'' by Creutz. et. al

open access: yes, 1997
The main construction of the paper in the title [hep-lat/9612017] is summarized using more standard particle physics language. Also, a flaw is pointed out and several objections to the more general thoughts expressed by Creutz et. al. are raised.Comment:
't Hooft   +15 more
core   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

The State of Ukrainian after the Regaining of Independence by Ukraine in August 1991

open access: yesPółrocznik Językoznawczy Tertium, 2016
The article discusses changes in Ukrainian after Ukraine had regained independence. Prior to 1991, the Soviet authorities – apart from various prohibitions known from the time of Russian tsars – had created a system of interfering in internal laws of ...
Bożena Zinkiewicz-Tomanek
doaj   +1 more source

Proposal for encoding the Elbasan script in the SMP of the UCS [PDF]

open access: yes, 2011
This is a proposal to encode the Elbasan script in the international character encoding standard Unicode. This script was published in Unicode Standard version 7.0 in June 2014. The Elbasan script is attested in the Elbasan Gospel manuscript, which dates
Elsie, Robert, Everson, Michael
core   +1 more source

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