Results 101 to 110 of about 1,177,924 (224)
Towards Standards-Compliant Assistive Technology Product Specifications via LLMs [PDF]
In the rapidly evolving field of assistive technology (AT), ensuring that products meet national and international standards is essential for user safety, efficacy, and accessibility. In this vision paper, we introduce CompliAT, a pioneering framework designed to streamline the compliance process of AT product specifications with these standards ...
arxiv +1 more source
FEBS Letters, EarlyView.We achieved cytoplasmic delivery of non‐cell‐penetrating IgGs by grafting a single functional complementarity‐determining region 1 (CDR1) from the light chain variable region (VL) of the cell‐internalizable 3D8 antibody. The engineered IgG acquired cell‐penetrating ability while maintaining antigen affinity, highlighting CDR1 grafting as a promising ...
Yerin Jeon +5 more
wiley +1 more source
The rare radiative decay $B_s \to ν\barν γ$ in beyond Standard Model scenarios [PDF]
arXiv, 2002 In this paper, I study the branching ratio of the rare radiative decay $B_s \to \nu \bar{\nu} \gamma$ in the framework of the Fourth-Generation Standard Model and the Two-Higgs-Doublet Model. It is shown that this quantity is a very effective tool for establishing new physics beyond the Standard Model.
arxiv
Ion channel function of polycystin‐2/polycystin‐1 heteromer revealed by structure‐guided mutagenesis
FEBS Letters, EarlyView.Mutations in polycystin‐1 (PC1) or polycystin‐2 (PC2) cause autosomal‐dominant polycystic kidney disease (ADPKD). We generated a novel gain‐of‐function PC2/PC1 heteromeric ion channel by mutating pore‐blocking residues. Moreover, we demonstrated that PC2 will preferentially assemble with PC1 to form heteromeric complexes when PC1 is co‐expressed ...
Tobias Staudner +7 more
wiley +1 more source
CP violation in the standard model with four generations [PDF]
, 1987 Dan–di Wu, Cern-Geneva, Yue-Liang Wu
openalex +1 more source
Autophagy in cancer and protein conformational disorders
FEBS Letters, EarlyView.Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley +1 more source
Effective lagrangian description of the possible strong sector of the standard model [PDF]
, 1984 R. Casalbuoni, D. Dominici, R. Gatto
openalex +1 more source
FEBS Letters, EarlyView.The protonated form of butyrate, as well as other short‐chain fatty acids (SCFAs), is membrane permeable. In acidic extracellular environments, this can lead to intracellular accumulation of SCFAs and cytosolic acidification. This phenomenon will be particularly relevant in acidic environments such as the large intestine or tumor microenvironments ...
Muwei Jiang +2 more
wiley +1 more source
Non-standard 2D critical statistical models from Liouville theory [PDF]
, 1985 J.-L. Gervais, A. Neveu
openalex +1 more source
Brucella NyxA and NyxB dimerization enhances effector function during infection
FEBS Letters, EarlyView.Brucella abortus thrives inside cells thanks to the translocation of effector proteins that fine‐tune cellular functions. NyxA and NyxB are two effectors that destabilize the nucleolar localization of their host target, SENP3. We show that the Nyx proteins directly interact with each other and that their dimerization is essential for their function ...
Lison Cancade‐Veyre +4 more
wiley +1 more source