Results 301 to 310 of about 11,075,264 (337)

A subset of MMR‐proficient colon cancers responds to neoadjuvant immunotherapy

open access: yesMolecular Oncology, EarlyView.
Tan et al. reveal that a distinct subset of early‐stage pMMR colon cancers can respond to neoadjuvant immunotherapy. In the NICHE‐2 trial, responders (26%) were characterized by chromosomal instability, TP53 mutations, and proliferative cell‐cycle programs, whereas nonresponders showed metabolic and stromal reprogramming with TGF‐β‐driven ...
Eleonora Piumatti   +3 more
wiley   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

Time course of log IL-6 over time among the L, I and H phenotypes. Values are means plus/minus standard deviations. Negative values are possible because they are predicted values. For each phenotype, 5 time points were considered (D1, D7, D14, D21, D28). Linear mixed model, p=0.175.

open access: green
Nicolas Partouche (17777862)   +9 more
openalex   +1 more source

Models, Standards, Guidelines

Clinics in Geriatric Medicine, 2005
This article reviews the current illness experience for elders, highlights key issues that cause suffering and affect the quality of life of elders in our society, and reviews the definition and the process for providing palliative care. A consensus-building process is described, which any hospice or palliative care organization can use to adapt ...
Frank D, Ferris, S Lawrence, Librach
openaire   +2 more sources

Ununifying the standard model

Physical Review Letters, 1989
We present an electroweak theory in which left-handed quarks and leptons transform as doublets under separate SU(2) gauge groups. Spontaneous symmetry breakdown results in two charged and two neutral massive vector bosons. The lightest charged and neutral gauge bosons behave like the /ital W/ and /ital Z/ of the standard SU(2)/times/U(1) electroweak ...
, Georgi, , Jenkins, , Simmons
openaire   +2 more sources

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