Results 81 to 90 of about 1,177,924 (224)
FEBS Letters, EarlyView.Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma +8 more
wiley +1 more source
The Top-Quark Mass: Challenges in Definition and Determination
Frontiers in Physics, 2019 The top-quark mass is a parameter of paramount importance in particle physics, playing a crucial role in the electroweak precision tests and in the stability of the Standard Model vacuum.
Gennaro Corcella
doaj +1 more source
The power of microRNA regulation—insights into immunity and metabolism
FEBS Letters, EarlyView.MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto +2 more
wiley +1 more source
A Novel Identity-Based Signcryption Scheme in the Standard Model
Information, 2017 Identity-based signcryption is a useful cryptographic primitive that provides both authentication and confidentiality for identity-based crypto systems. It is challenging to build a secure identity-based signcryption scheme that can be proven secure in a
Yueying Huang, Junjie Yang
doaj +1 more source
Identification of novel small molecule inhibitors of ETS transcription factors
FEBS Letters, EarlyView.ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla +9 more
wiley +1 more source
EntropyIn this brief paper, I give a very personal account on the state of particle physics on the occasion of Paul Frampton’s 80th birthday.
Xavier Calmet
doaj +1 more source
Towards an Improved Test of the Standard Model’s Most Precise Prediction
Atoms, 2019 The electron and positron magnetic moments are the most precise prediction of the standard model of particle physics. The most accurate measurement of a property of an elementary particle has been made to test this result.
G. Gabrielse +3 more
doaj +1 more source
Erratum to: Comparison of the potential coefficient models of the Standard Earth (II and III) and the GEM 5 and GEM 6 [PDF]
, 1975 Richard H. Rapp
openalex +1 more source
The Saccharomyces cerevisiae amino acid transporter Lyp1 has a broad substrate spectrum
FEBS Letters, EarlyView.In Saccharomyces cerevisiae, Yeast Amino acid Transporter family members mediate the import of amino acids, ranging from substrate specialists to generalists. Here, we show that the specialist transporter, Lyp1, has a broader substrate spectrum than previously described, with affinity constants spanning from micromolar to millimolar.
Foteini Karapanagioti +3 more
wiley +1 more source
A Note on "How Robust Standard Errors Expose Methodological Problems They Do Not Fix, and What to Do About It" [PDF]
arXiv, 2016 King and Roberts (2015, KR) claim that a disagreement between robust and classical standard errors exposes model misspecification. We emphasize that KR's claim only generally applies to parametric models: models that assume a restrictive form of the distribution of the outcome. Many common models in use in political science, including the linear model,
arxiv