Results 171 to 180 of about 2,868,112 (314)

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

The Impact of Interaction Standard Theory-Based Multi-Care on Postpartum Recovery, Coping Styles, Psychological Distress, and Quality of Life in Women with Postpartum Hemorrhage

Feifei Meng,1,* Yufan Yuan,2,* Xingxing Lv3 1Department of Public Health, Shijiazhuang Obstetrics and Gynecology Hospital, Shijiazhuang, Hebei, People’s Republic of China; 2Department of Nursing, Shijiazhuang Obstetrics and Gynecology ...
Meng F, Lv X, Yuan Y
core  

Accommodation with anticancer drug shortage: A Lebanese harmful solution

Frontiers in Oncology, 2023
Clarisse Kattan, Joseph Kattan
doaj   +1 more source

A Geographic Disparities Analysis Between Standard of Care and Clinical Trial CAR-T Patients in Kansas. [PDF]

Cancer Med
Pepper S, Rashid A, Tabak C, Ratnayake I, Rahman MM, Talukder MRI, McGuirk M, Rippee O, McGuirk J, Hoffmann M, Sung AD, Ahmed N, Mudaranthakam DP.   +12 more
europepmc   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Screening for liver disease in patients with diabetes: new standard of care? [PDF]

Proc (Bayl Univ Med Cent)
Iyer M, Asrani SK.
europepmc   +1 more source

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Cost-effectiveness of stem cell therapy versus standard of care for acute and subacute ischemic stroke. [PDF]

PLoS One
Takamiya S, Morii Y, Osanai T, Ohashi K, Ogasawara K, Houkin K, Fujimura M.   +6 more
europepmc   +1 more source

Standards of care: The value and importance of standardization [PDF]

Arthritis & Rheumatism, 1997
J S, Smolen, G, Steiner, E M, Tan
openaire   +2 more sources