Results 151 to 160 of about 6,793,295 (290)

Estimation of operational value-at-risk in the presence of minimum collection threshold: An empirical study [PDF]

The recently finalized Basel II Capital Accord requires banks to adopt a procedure to estimate the operational risk capital charge. Under the Advanced Measurement Approaches, that are currently mandated for all large internationally active US banks ...
Rachev, Svetlozar T., Chernobai, Anna, Menn, Christian, Trück, Stefan   +3 more
core  

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

FEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil, Jeffrey A. Hawkes, Cecilia Blikstad, Pia Lindberg   +3 more
wiley   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Daytime Idle Energy Reduction in Radiotherapy Simulation Computed Tomography: A Prospective Workflow-Based Evaluation. [PDF]

J Med Radiat Sci
Hirotaki K, Honda Y, Ito M.
europepmc   +1 more source

Operational modal analysis from flight test data

, 2013
In the framework of the operational modal analysis (OMA), several approaches have been developed for estimating the modal parameters, i.e., natural frequencies, damping ratios, and mode shapes.
COPPOTELLI, Giuliano, D. Tozzi, GRAPPASONNI, CHIARA   +2 more
core  

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

Seawater pH Measurement: A Critical Metrological Assessment of Operational Scales and the Unified pH Scale. [PDF]

Sensors (Basel)
Quendera R, Nunes MJ, Fernando AL, Palma C, Giza MS, Pellegrino O, Alves E Sousa J.   +6 more
europepmc   +1 more source

An Aggregated Information Technology Checklist for Operational Risk Management [PDF]

This study addresses the issue of the Information Technology (IT) Governance frameworks and standards that respond to different levels of operational risks, especially those caused by the information systems and technology infrastructure.
Mehmet Zeki Önal
core  

Smaller is better: nanobodies meet NMR

FEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Beyond Blind Trust in Hospital Data Warehouses: Evaluating Real-World Data Accountability. [PDF]

Learn Health Syst
Morohashi A, Yamashita S, Imaizumi T, Sano T, Kuwatsuka Y, Ando M, Shiratori Y.   +6 more
europepmc   +1 more source