Results 241 to 250 of about 6,793,295 (290)

The impact of leukocyte‐associated RNA retention on platelet RNA‐based cancer detection

Molecular Oncology, EarlyView.
Platelets carry RNA signals that may help detect cancer, but platelet samples can also retain RNA from white blood cells. We found that this retained white blood cell signal did not significantly affect machine learning cancer classification, suggesting that the cancer‐related RNA signal in platelets is largely independent of leukocyte‐associated RNA ...
Michał Sieczczyński, Krzysztof Pastuszak, Anna Samelak‐Czajka, Zuzanna Cemka, Paulina Jackowiak, Tomasz Stefaniak, Sylwia Łapińska‐Szumczyk, Jacek Jassem, Anna J. Żaczek, Matthew T. Rondina, Myron G. Best, Sjors G. J. G. In 't Veld, Anna Supernat   +12 more
wiley   +1 more source

Plug-and-play coaxial nested-tube supported liquid membrane extraction for the determination of nonsteroidal anti-inflammatory drugs in human plasma. [PDF]

RSC Adv
Huang H, Lv M, Wang Q, Zhang Q, Yang Y, Chen D, Qin Z.   +6 more
europepmc   +1 more source

Overcoming platinum resistance by the disulfiram metabolite CuET in novel preclinical models of human carcinomas

Molecular Oncology, EarlyView.
Cisplatin‐resistant cancer cells survive DNA‐damaging platinum‐based treatment yet remain sensitive to CuET‐induced proteotoxic stress. The distinct mechanism of action allows CuET to overcome and eliminate cisplatin‐resistant tumour cells, unless highly expressed metallothioneins (MTs) interfere with CuET, thereby highlighting MT levels as candidate ...
Stefanos Arampatzis, Tereza Buchtová, Jirina Bartkova, Marie Lund Bay, Christoffer Lynge Halvorsen, Zuzana Machacova, Zdenek Skrott, Martin Mistrik, Ekaterina Dulina, Miguel Andujar‐Sanchez, Estrid Høgdall, Tine Henrichsen Schnack, Claus Høgdall, Berit Jul Mosgaard, Marie Boennelycke, Jacob Brink Laursen, Allan Jensen, Susanne K. Kjær, Tuula Kallunki, Robert Strauss, Jiri Bartek   +20 more
wiley   +1 more source

Ultrasound Archiving in the Emergency Department: Implementation, Governance and 4-Year Outcomes at an Australian Tertiary Emergency Department. [PDF]

Emerg Med Australas
Manivel V, Mirmiran B, Helm C, Hastings C.   +3 more
europepmc   +1 more source

An outer membrane vesicle‐associated two‐track model for enterotoxigenic Bacteroides fragilis oncogenesis

Molecular Oncology, EarlyView.
Enterotoxigenic Bacteroides fragilis is a gut bacterium linked to bowel cancer. We propose that its toxin acts along two routes: at the cell surface, cutting the adhesion protein E‐cadherin and triggering inflammation; and inside the cell, delivered by bacterial vesicles, switching on NOD1 and cancer stem cell programs.
Kangchan Choi, Sang‐Hyeon Yoo, Ki‐Jong Rhee   +2 more
wiley   +1 more source

Artificial Intelligence Literacy Among Students in Health-Related Academic Programs at Tabriz University of Medical Sciences: A Multidimensional Assessment. [PDF]

Adv Med Educ Pract
Mahami-Oskouei M, Gavgani VZ, Hosseinifard H.   +2 more
europepmc   +1 more source

An Uncertainty-Robust Decision Framework Based on Fractional Einstein Aggregation for Prioritizing Renewable Power Generation Technologies with Unknown Weights. [PDF]

Entropy (Basel)
Albaity M, Rahim M.
europepmc   +1 more source

Improving governance of waiting list management in a CAMHS neurodevelopmental service using a digital workflow: a quality improvement project. [PDF]

BMJ Open Qual
Willmott R.
europepmc   +1 more source

Causes of Elective Surgery Procedure Cancellation in a Portuguese General Hospital: A Cross-Sectional Observational Study. [PDF]

Cureus
Cunha F, Baptista I, Inês Andrade M, Castro Leal I, Chalo D.   +4 more
europepmc   +1 more source