ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan +9 more
wiley +1 more source
Mechanical Performance and Marginal Integrity Evaluation of Contemporary Universal Resin Composites for Dental Restorations: An In-Vitro Study. [PDF]
Ali Shah S.
europepmc +1 more source
Artificial intelligence and image processing framework for automated airway invasion detection and residue classification from swallowing endoscopy. [PDF]
Araújo L +8 more
europepmc +1 more source
Effect of preendodontic build-up on irrigant penetration in extracted single-rooted premolars: An <i>ex vivo</i> study. [PDF]
Fuke SG +3 more
europepmc +1 more source
Neuroergonomic evaluation of risk-warning eHMI penetration rates in vehicle platoons: effects on pedestrians' mental workload, situation awareness, and gap acceptance. [PDF]
Yang F +7 more
europepmc +1 more source
Rapid 3D Measurement of Tire-Pavement True Contact Texture and Its Implications for Skid Resistance. [PDF]
Mamat T, Cheng S, Xu L, Xiao S, He C.
europepmc +1 more source
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The Dynamic Penetration Test: A Standard that is not Standardized
Géotechnique, 1970Synopsis The Paper presents a description and a discussion of the technique of making the so-called standard penetration test as used in North and South America. Dynamic penetration tests such as the SPT are used widely in an effort to get results that can be interpreted by engineers on a universal basis.
H. O. Ireland, O. Moretto, M. Vargas
openaire +1 more source

