Results 51 to 60 of about 2,222,592 (283)

An orbit determination method of spacecraft based on distribution regression

Open Astronomy, 2021
A new method of orbit determination (OD) is proposed: distribution regression. The paper focuses on the process of using sparse observation data to determine the orbit of the spacecraft without any prior information. The standard regression process is to
Jiang Chunsheng
doaj   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Multidisciplinary Design Optimization of Unmanned Aerial Vehicle under Uncertainty

Journal of Aerospace Technology and Management, 2017
Uncertainty-based multidisciplinary design optimization considers probabilistic variables and parameters and provides an approach to account for sources of uncertainty in design optimization.
Majid Hosseini, Mehran Nosratollahi, Hossein Sadati   +2 more
doaj  

Space-Time Codes for Wireless Optical Communications

EURASIP Journal on Advances in Signal Processing, 2002
A space-time channel coding technique is presented for overcoming turbulence-induced fading in an atmospheric optical heterodyne communication system that uses multiple transmit and receive apertures. In particular, a design criterion for minimizing the
Tarokh Vahid, Haas Shane M, Shapiro Jeffrey H   +2 more
doaj   +1 more source

Statistical predictions for the dynamics of a low-speed system: Newtonian versus special-relativistic mechanics. [PDF]

PLoS ONE, 2012
The newtonian and special-relativistic statistical predictions for the mean, standard deviation and probability density function of the position and momentum are compared for the periodically-delta-kicked particle at low speed.
Shiuan-Ni Liang, Boon Leong Lan
doaj   +1 more source

Multiscale functional inequalities in probability: Constructive approach

Annales Henri Lebesgue, 2017
Consider an ergodic stationary random field $A$ on the ambient space $\mathbb R^d$. In order to establish concentration properties for nonlinear functions $Z(A)$, it is standard to appeal to functional inequalities like Poincare or logarithmic Sobolev ...
Mitia Duerinckx, A. Gloria
semanticscholar   +1 more source